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Compound heterozygous SPATA5 variants in four families and functional studies of SPATA5 deficiency.
Puusepp S, Kovacs-Nagy R, Alhaddad B, Braunisch M, Hoffmann GF, Kotzaeridou U, Lichvarova L, Liiv M, Makowski C, Mandel M, Meitinger T, Pajusalu S, Rodenburg RJ, Safiulina D, Strom TM, Talvik I, Vaarmann A, Wilson C, Kaasik A, Haack TB, Õunap K. Puusepp S, et al. Among authors: mandel m. Eur J Hum Genet. 2018 Mar;26(3):407-419. doi: 10.1038/s41431-017-0001-6. Epub 2018 Jan 17. Eur J Hum Genet. 2018. PMID: 29343804 Free PMC article.
Mitochondrial biogenesis is required for axonal growth.
Vaarmann A, Mandel M, Zeb A, Wareski P, Liiv J, Kuum M, Antsov E, Liiv M, Cagalinec M, Choubey V, Kaasik A. Vaarmann A, et al. Among authors: mandel m. Development. 2016 Jun 1;143(11):1981-92. doi: 10.1242/dev.128926. Epub 2016 Apr 27. Development. 2016. PMID: 27122166
Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome.
Cagalinec M, Liiv M, Hodurova Z, Hickey MA, Vaarmann A, Mandel M, Zeb A, Choubey V, Kuum M, Safiulina D, Vasar E, Veksler V, Kaasik A. Cagalinec M, et al. Among authors: mandel m. PLoS Biol. 2016 Jul 19;14(7):e1002511. doi: 10.1371/journal.pbio.1002511. eCollection 2016 Jul. PLoS Biol. 2016. PMID: 27434582 Free PMC article.
Miro proteins prime mitochondria for Parkin translocation and mitophagy.
Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A. Safiulina D, et al. Among authors: mandel m. EMBO J. 2019 Jan 15;38(2):e99384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30. EMBO J. 2019. PMID: 30504269 Free PMC article.
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome.
Liiv M, Vaarmann A, Safiulina D, Choubey V, Gupta R, Kuum M, Janickova L, Hodurova Z, Cagalinec M, Zeb A, Hickey MA, Huang YL, Gogichaishvili N, Mandel M, Plaas M, Vasar E, Loncke J, Vervliet T, Tsai TF, Bultynck G, Veksler V, Kaasik A. Liiv M, et al. Among authors: mandel m. Nat Commun. 2024 Jul 21;15(1):6143. doi: 10.1038/s41467-024-50502-x. Nat Commun. 2024. PMID: 39034309 Free PMC article.
Gene expression patterns and environmental enrichment-induced effects in the hippocampi of mice suggest importance of Lsamp in plasticity.
Heinla I, Leidmaa E, Kongi K, Pennert A, Innos J, Nurk K, Tekko T, Singh K, Vanaveski T, Reimets R, Mandel M, Lang A, Lilleväli K, Kaasik A, Vasar E, Philips MA. Heinla I, et al. Among authors: mandel m. Front Neurosci. 2015 Jun 8;9:205. doi: 10.3389/fnins.2015.00205. eCollection 2015. Front Neurosci. 2015. PMID: 26136648 Free PMC article.
Indole-like Trk receptor antagonists.
Tammiku-Taul J, Park R, Jaanson K, Luberg K, Dobchev DA, Kananovich D, Noole A, Mandel M, Kaasik A, Lopp M, Timmusk T, Karelson M. Tammiku-Taul J, et al. Among authors: mandel m. Eur J Med Chem. 2016 Oct 4;121:541-552. doi: 10.1016/j.ejmech.2016.06.003. Epub 2016 Jun 4. Eur J Med Chem. 2016. PMID: 27318978
676 results