Nickels ML - Search Results

1

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Among authors: nickels ml. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.

2

A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.

Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC. Hight MR, et al. Among authors: nickels ml. Clin Cancer Res. 2014 Apr 15;20(8):2126-35. doi: 10.1158/1078-0432.CCR-13-2444. Epub 2014 Feb 26. Clin Cancer Res. 2014. PMID: 24573549 Free PMC article.

3

Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer.

Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC. Hassanein M, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Feb;18(1):18-23. doi: 10.1007/s11307-015-0862-4. Mol Imaging Biol. 2016. PMID: 25971659 Free PMC article.

4

New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO.

Li J, Schulte ML, Nickels ML, Manning HC. Li J, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3472-7. doi: 10.1016/j.bmcl.2016.06.041. Epub 2016 Jun 16. Bioorg Med Chem Lett. 2016. PMID: 27353534 Free PMC article.

5

Optimized Translocator Protein Ligand for Optical Molecular Imaging and Screening.

Li J, Smith JA, Dawson ES, Fu A, Nickels ML, Schulte ML, Manning HC. Li J, et al. Among authors: nickels ml. Bioconjug Chem. 2017 Apr 19;28(4):1016-1023. doi: 10.1021/acs.bioconjchem.6b00711. Epub 2017 Feb 13. Bioconjug Chem. 2017. PMID: 28156095

6

Automated radiosynthesis of 5-[¹¹C]l-glutamine, an important tracer for glutamine utilization.

Rosenberg AJ, Nickels ML, Schulte ML, Manning HC. Rosenberg AJ, et al. Among authors: nickels ml. Nucl Med Biol. 2018 Dec;67:10-14. doi: 10.1016/j.nucmedbio.2018.09.002. Epub 2018 Oct 15. Nucl Med Biol. 2018. PMID: 30359787 Free PMC article.

7

Utility of [¹⁸F]FSPG PET to Image Hepatocellular Carcinoma: First Clinical Evaluation in a US Population.

Kavanaugh G, Williams J, Morris AS, Nickels ML, Walker R, Koglin N, Stephens AW, Washington MK, Geevarghese SK, Liu Q, Ayers D, Shyr Y, Manning HC. Kavanaugh G, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Dec;18(6):924-934. doi: 10.1007/s11307-016-1007-0. Mol Imaging Biol. 2016. PMID: 27677886 Free PMC article. Clinical Trial.

8

DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer.

Luo N, Nixon MJ, Gonzalez-Ericsson PI, Sanchez V, Opalenik SR, Li H, Zahnow CA, Nickels ML, Liu F, Tantawy MN, Sanders ME, Manning HC, Balko JM. Luo N, et al. Among authors: nickels ml. Nat Commun. 2018 Jan 16;9(1):248. doi: 10.1038/s41467-017-02630-w. Nat Commun. 2018. PMID: 29339738 Free PMC article.

9

Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (¹⁸F-VUIIS1018A) to Image Glioma.

Tang D, Li J, Nickels ML, Huang G, Cohen AS, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2019 Feb;21(1):113-121. doi: 10.1007/s11307-018-1198-7. Mol Imaging Biol. 2019. PMID: 29869061 Free PMC article.

10

The Current Role of Microfluidics in Radiofluorination Chemistry.

Knapp KA, Nickels ML, Manning HC. Knapp KA, et al. Among authors: nickels ml. Mol Imaging Biol. 2020 Jun;22(3):463-475. doi: 10.1007/s11307-019-01414-6. Mol Imaging Biol. 2020. PMID: 31485889 Review.

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