Ludwig T - Search Results

1

BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.

Vázquez-Arreguín K, Maddox J, Kang J, Park D, Cano RR, Factor RE, Ludwig T, Tantin D. Vázquez-Arreguín K, et al. Among authors: ludwig t. Mol Cancer Res. 2018 Mar;16(3):439-452. doi: 10.1158/1541-7786.MCR-17-0364. Epub 2018 Jan 12. Mol Cancer Res. 2018. PMID: 29330289 Free PMC article.

2

Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.

Park D, Bergin SM, Jones D, Ru P, Koivisto CS, Jeon YJ, Sizemore GM, Kladney RD, Hadjis A, Shakya R, Ludwig T. Park D, et al. Among authors: ludwig t. Cancer Res. 2020 Oct 1;80(19):4172-4184. doi: 10.1158/0008-5472.CAN-20-0486. Epub 2020 Jul 30. Cancer Res. 2020. PMID: 32732220

3

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.

Park D, Shakya R, Koivisto C, Pitarresi JR, Szabolcs M, Kladney R, Hadjis A, Mace TA, Ludwig T. Park D, et al. Among authors: ludwig t. PLoS One. 2019 Dec 26;14(12):e0226714. doi: 10.1371/journal.pone.0226714. eCollection 2019. PLoS One. 2019. PMID: 31877165 Free PMC article.

4

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.

Reid LJ, Shakya R, Modi AP, Lokshin M, Cheng JT, Jasin M, Baer R, Ludwig T. Reid LJ, et al. Among authors: ludwig t. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20876-81. doi: 10.1073/pnas.0811203106. Epub 2008 Dec 16. Proc Natl Acad Sci U S A. 2008. PMID: 19088202 Free PMC article.

5

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.

Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Science. 2011 Oct 28;334(6055):525-8. doi: 10.1126/science.1209909. Science. 2011. PMID: 22034435 Free PMC article.

6

The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity.

Baer R, Ludwig T. Baer R, et al. Among authors: ludwig t. Curr Opin Genet Dev. 2002 Feb;12(1):86-91. doi: 10.1016/s0959-437x(01)00269-6. Curr Opin Genet Dev. 2002. PMID: 11790560 Review.

7

Stromal PTEN determines mammary epithelial response to radiotherapy.

Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, Yu L, Fernandez SA, Chakravarti A, Shields PG, White JR, Yee LD, Rosol TJ, Ludwig T, Park M, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: ludwig t. Nat Commun. 2018 Jul 17;9(1):2783. doi: 10.1038/s41467-018-05266-6. Nat Commun. 2018. PMID: 30018330 Free PMC article.

8

The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.

Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, Murty V, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Proc Natl Acad Sci U S A. 2008 May 13;105(19):7040-5. doi: 10.1073/pnas.0711032105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443292 Free PMC article.

9

The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression.

Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J, Bruce S, Bruce R, Shakya R, Ludwig T, Rosenfeld S, Sims PA, Bruce JN, Califano A, Canoll P. Sonabend AM, et al. Among authors: ludwig t. Cancer Res. 2014 Mar 1;74(5):1440-1451. doi: 10.1158/0008-5472.CAN-13-2150. Epub 2014 Jan 3. Cancer Res. 2014. PMID: 24390738 Free PMC article.

10

The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

Wu-Baer F, Ludwig T, Baer R. Wu-Baer F, et al. Among authors: ludwig t. Mol Cell Biol. 2010 Jun;30(11):2787-98. doi: 10.1128/MCB.01056-09. Epub 2010 Mar 29. Mol Cell Biol. 2010. PMID: 20351172 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

426 results

Search Page

Filters