Zhu J - Search Results

1

Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.

Wei H, Mao F, Ni S, Chen F, Li B, Qiu X, Hu L, Wang M, Zheng X, Zhu J, Lan L, Li J. Wei H, et al. Among authors: zhu j. Eur J Med Chem. 2018 Feb 10;145:235-251. doi: 10.1016/j.ejmech.2017.12.090. Epub 2017 Dec 29. Eur J Med Chem. 2018. PMID: 29328999

2

Synthesis of 3-substituted 1,5-aldehyde esters via an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals.

Deng J, Wang F, Yan W, Zhu J, Jiang H, Wang W, Li J. Deng J, et al. Among authors: zhu j. Chem Commun (Camb). 2012 Jan 4;48(1):148-50. doi: 10.1039/c1cc15714k. Epub 2011 Nov 7. Chem Commun (Camb). 2012. PMID: 22057586

3

Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent.

Huang H, Lu W, Li X, Cong X, Ma H, Liu X, Zhang Y, Che P, Ma R, Li H, Shen X, Jiang H, Huang J, Zhu J. Huang H, et al. Among authors: zhu j. Bioorg Med Chem Lett. 2012 Jan 15;22(2):958-62. doi: 10.1016/j.bmcl.2011.12.011. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22192590

4

Synthesis, structure-activity relationship, and pharmacophore modeling studies of pyrazole-3-carbohydrazone derivatives as dipeptidyl peptidase IV inhibitors.

Wu D, Jin F, Lu W, Zhu J, Li C, Wang W, Tang Y, Jiang H, Huang J, Liu G, Li J. Wu D, et al. Among authors: zhu j. Chem Biol Drug Des. 2012 Jun;79(6):897-906. doi: 10.1111/j.1747-0285.2012.01365.x. Epub 2012 Mar 21. Chem Biol Drug Des. 2012. PMID: 22381062

5

Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.

Deng J, Li N, Liu H, Zuo Z, Liew OW, Xu W, Chen G, Tong X, Tang W, Zhu J, Zuo J, Jiang H, Yang CG, Li J, Zhu W. Deng J, et al. Among authors: zhu w, zhu j. J Med Chem. 2012 Jul 26;55(14):6278-93. doi: 10.1021/jm300146f. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22742496

6

Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists.

Huang H, Yu Y, Gao Z, Zhang Y, Li C, Xu X, Jin H, Yan W, Ma R, Zhu J, Shen X, Jiang H, Chen L, Li J. Huang H, et al. Among authors: zhu j. J Med Chem. 2012 Aug 23;55(16):7037-53. doi: 10.1021/jm3002718. Epub 2012 Aug 10. J Med Chem. 2012. PMID: 22862148

7

1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: a novel cyclophilin A allosteric activator.

Lv M, Shi T, Mao X, Li X, Chen Y, Zhu J, Ni S, Shen X, Jiang H, Li J, Zhang J, Huang J. Lv M, et al. Among authors: zhu j. Biochem Biophys Res Commun. 2012 Sep 7;425(4):938-43. doi: 10.1016/j.bbrc.2012.08.014. Epub 2012 Aug 11. Biochem Biophys Res Commun. 2012. PMID: 22906739

8

The ethylene bis-dithiocarbamate fungicide Mancozeb activates voltage-gated KCNQ2 potassium channel.

Li P, Zhu J, Kong Q, Jiang B, Wan X, Yue J, Li M, Jiang H, Li J, Gao Z. Li P, et al. Among authors: zhu j. Toxicol Lett. 2013 Jun 7;219(3):211-7. doi: 10.1016/j.toxlet.2013.03.020. Epub 2013 Mar 28. Toxicol Lett. 2013. PMID: 23542819

9

A strategy enabling enantioselective direct conjugate addition of inert aryl methane nucleophiles to enals with a chiral amine catalyst under mild conditions.

Li T, Zhu J, Wu D, Li X, Wang S, Li H, Li J, Wang W. Li T, et al. Among authors: zhu j. Chemistry. 2013 Jul 8;19(28):9147-50. doi: 10.1002/chem.201300304. Epub 2013 May 24. Chemistry. 2013. PMID: 23712495 No abstract available.

10

Discovery of new imidazole derivatives containing the 2,4-dienone motif with broad-spectrum antifungal and antibacterial activity.

Liu C, Shi C, Mao F, Xu Y, Liu J, Wei B, Zhu J, Xiang M, Li J. Liu C, et al. Among authors: zhu j. Molecules. 2014 Sep 29;19(10):15653-72. doi: 10.3390/molecules191015653. Molecules. 2014. PMID: 25268720 Free PMC article.

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