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The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, Öberg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Grønborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honoré C, Ahnfelt-Rønne J, Hecksher-Sørensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. Tsonkova VG, et al. Among authors: wolf xa. Mol Metab. 2018 Feb;8:144-157. doi: 10.1016/j.molmet.2017.12.007. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29307512 Free PMC article.
Semantic text mining in early drug discovery for type 2 diabetes.
Hansson LK, Hansen RB, Pletscher-Frankild S, Berzins R, Hansen DH, Madsen D, Christensen SB, Christiansen MR, Boulund U, Wolf XA, Kjærulff SK, van de Bunt M, Tulin S, Jensen TS, Wernersson R, Jensen JN. Hansson LK, et al. Among authors: wolf xa. PLoS One. 2020 Jun 15;15(6):e0233956. doi: 10.1371/journal.pone.0233956. eCollection 2020. PLoS One. 2020. PMID: 32542027 Free PMC article.