Froese JT - Search Results

1

Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics.

Earl DC, Ferrell PB Jr, Leelatian N, Froese JT, Reisman BJ, Irish JM, Bachmann BO. Earl DC, et al. Among authors: froese jt. Nat Commun. 2018 Jan 2;9(1):39. doi: 10.1038/s41467-017-02470-8. Nat Commun. 2018. PMID: 29295987 Free PMC article.

2

Development and application of a high throughput assay system for the detection of Rieske dioxygenase activity.

Preston-Herrera C, Jackson AS, Bachmann BO, Froese JT. Preston-Herrera C, et al. Among authors: froese jt. Org Biomol Chem. 2021 Jan 28;19(4):775-784. doi: 10.1039/d0ob02412k. Epub 2021 Jan 13. Org Biomol Chem. 2021. PMID: 33439179

3

Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins.

Yñigez-Gutierrez AE, Wurm JE, Froese JT, Rosenthal NE, Bachmann BO. Yñigez-Gutierrez AE, et al. Among authors: froese jt. ACS Chem Biol. 2024 Feb 16;19(2):526-535. doi: 10.1021/acschembio.3c00693. Epub 2024 Jan 30. ACS Chem Biol. 2024. PMID: 38289021

4

Palladium-catalyzed carbonylation of halo arene-cis-dihydrodiols to the corresponding carboxylates. Access to compounds unavailable by toluene dioxygenase-mediated dihydroxylation of the corresponding benzoate esters.

Froese J, Hudlicky JR, Hudlicky T. Froese J, et al. Org Biomol Chem. 2014 Oct 21;12(39):7810-9. doi: 10.1039/c4ob01417k. Epub 2014 Aug 26. Org Biomol Chem. 2014. PMID: 25158114

5

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast.

Qu Y, Easson ML, Froese J, Simionescu R, Hudlicky T, De Luca V. Qu Y, et al. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6224-9. doi: 10.1073/pnas.1501821112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918424 Free PMC article.

6

Chemoenzymatic Synthesis of Pleiogenone A: An Antiproliferative Trihydroxyalkylcyclohexenone Isolated from Pleiogynium timorense.

Froese J, Overbeeke C, Hudlicky T. Froese J, et al. Chemistry. 2016 Apr 25;22(18):6180-4. doi: 10.1002/chem.201601061. Epub 2016 Apr 1. Chemistry. 2016. PMID: 26956129

7

Synthesis of Amaryllidaceae Constituents and Unnatural Derivatives.

Ghavre M, Froese J, Pour M, Hudlicky T. Ghavre M, et al. Angew Chem Int Ed Engl. 2016 May 4;55(19):5642-91. doi: 10.1002/anie.201508227. Epub 2016 Mar 11. Angew Chem Int Ed Engl. 2016. PMID: 26969844 Review.

8

A Formal Approach to Xylosmin and Flacourtosides E and F: Chemoenzymatic Total Synthesis of the Hydroxylated Cyclohexenone Carboxylic Acid Moiety of Xylosmin.

Ghavre M, Froese J, Murphy B, Simionescu R, Hudlicky T. Ghavre M, et al. Org Lett. 2017 Mar 3;19(5):1156-1159. doi: 10.1021/acs.orglett.7b00194. Epub 2017 Feb 10. Org Lett. 2017. PMID: 28186763

9

Chemoenzymatic Synthesis of Advanced Intermediates for Formal Total Syntheses of Tetrodotoxin.

Baidilov D, Rycek L, Trant JF, Froese J, Murphy B, Hudlicky T. Baidilov D, et al. Angew Chem Int Ed Engl. 2018 Aug 20;57(34):10994-10998. doi: 10.1002/anie.201804602. Epub 2018 May 30. Angew Chem Int Ed Engl. 2018. PMID: 29750851

10

Engineering of Rieske dioxygenase variants with improved cis-dihydroxylation activity for benzoates.

Betts PC, Blakely SJ, Rutkowski BN, Bender B, Klingler C, Froese JT. Betts PC, et al. Among authors: froese jt. Biotechnol Bioeng. 2024 Oct;121(10):3144-3154. doi: 10.1002/bit.28786. Epub 2024 Jul 1. Biotechnol Bioeng. 2024. PMID: 38951963

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