Gaedigk A - Search Results

1

Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.

Twist GP, Gaedigk A, Miller NA, Farrow EG, Willig LK, Dinwiddie DL, Petrikin JE, Soden SE, Herd S, Gibson M, Cakici JA, Riffel AK, Leeder JS, Dinakarpandian D, Kingsmore SF. Twist GP, et al. Among authors: gaedigk a. NPJ Genom Med. 2016 Jan 13;1:15007. doi: 10.1038/npjgenmed.2015.7. eCollection 2016. NPJ Genom Med. 2016. PMID: 29263805 Free PMC article.

2

Epitope mapping studies with human anti-cytochrome P450 3A antibodies.

Leeder JS, Gaedigk A, Lu X, Cook VA. Leeder JS, et al. Among authors: gaedigk a. Mol Pharmacol. 1996 Feb;49(2):234-43. Mol Pharmacol. 1996. PMID: 8632755

3

Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase.

Gaedigk A, Leeder JS, Grant DM. Gaedigk A, et al. DNA Cell Biol. 1997 Nov;16(11):1257-66. doi: 10.1089/dna.1997.16.1257. DNA Cell Biol. 1997. PMID: 9406998

4

Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions.

Leeder JS, Lu X, Timsit Y, Gaedigk A. Leeder JS, et al. Among authors: gaedigk a. Pharmacogenetics. 1998 Jun;8(3):211-25. doi: 10.1097/00008571-199806000-00004. Pharmacogenetics. 1998. PMID: 9682267

5

NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.

Gaedigk A, Tyndale RF, Jurima-Romet M, Sellers EM, Grant DM, Leeder JS. Gaedigk A, et al. Pharmacogenetics. 1998 Aug;8(4):305-13. doi: 10.1097/00008571-199808000-00004. Pharmacogenetics. 1998. PMID: 9731717

6

High frequency of CYP2D6 poor and "intermediate" metabolizers in black populations: a review and preliminary data.

Bradford LD, Gaedigk A, Leeder JS. Bradford LD, et al. Among authors: gaedigk a. Psychopharmacol Bull. 1998;34(4):797-804. Psychopharmacol Bull. 1998. PMID: 10513455 Review.

7

Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.

Streetman DS, Ellis RE, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr. Streetman DS, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 1999 Nov;66(5):535-41. doi: 10.1016/S0009-9236(99)70018-4. Clin Pharmacol Ther. 1999. PMID: 10579482 Clinical Trial.

8

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.

Gaedigk A, Gotschall RR, Forbes NS, Simon SD, Kearns GL, Leeder JS. Gaedigk A, et al. Pharmacogenetics. 1999 Dec;9(6):669-82. doi: 10.1097/01213011-199912000-00002. Pharmacogenetics. 1999. PMID: 10634130

9

Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations.

Gaedigk A, Casley WL, Tyndale RF, Sellers EM, Jurima-Romet M, Leeder JS. Gaedigk A, et al. Can J Physiol Pharmacol. 2001 Oct;79(10):841-7. Can J Physiol Pharmacol. 2001. PMID: 11697742

10

Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.

Abdel-Rahman SM, Leeder JS, Wilson JT, Gaedigk A, Gotschall RR, Medve R, Liao S, Spielberg SP, Kearns GL. Abdel-Rahman SM, et al. Among authors: gaedigk a. J Clin Pharmacol. 2002 Jan;42(1):24-9. doi: 10.1177/0091270002042001002. J Clin Pharmacol. 2002. PMID: 11808821

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