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Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor.
Vitiello GA, Medina BD, Zeng S, Bowler TG, Zhang JQ, Loo JK, Param NJ, Liu M, Moral AJ, Zhao JN, Rossi F, Antonescu CR, Balachandran VP, Cross JR, DeMatteo RP. Vitiello GA, et al. Clin Cancer Res. 2018 Feb 15;24(4):972-984. doi: 10.1158/1078-0432.CCR-17-2697. Epub 2017 Dec 15. Clin Cancer Res. 2018. PMID: 29246941 Free PMC article.
ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor.
Zeng S, Seifert AM, Zhang JQ, Kim TS, Bowler TG, Cavnar MJ, Medina BD, Vitiello GA, Rossi F, Loo JK, Param NJ, DeMatteo RP. Zeng S, et al. Among authors: vitiello ga. Oncotarget. 2017 Dec 11;8(69):114195-114209. doi: 10.18632/oncotarget.23173. eCollection 2017 Dec 26. Oncotarget. 2017. PMID: 29371979 Free PMC article.
Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors.
Zhang JQ, Zeng S, Vitiello GA, Seifert AM, Medina BD, Beckman MJ, Loo JK, Santamaria-Barria J, Maltbaek JH, Param NJ, Moral JA, Zhao JN, Balachandran V, Rossi F, Antonescu CR, DeMatteo RP. Zhang JQ, et al. Among authors: vitiello ga. Cancer Immunol Res. 2018 Apr;6(4):434-447. doi: 10.1158/2326-6066.CIR-17-0345. Epub 2018 Feb 21. Cancer Immunol Res. 2018. PMID: 29467128 Free PMC article.
The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor.
Zhang JQ, Bosbach B, Loo JK, Vitiello GA, Zeng S, Seifert AM, Medina BD, Param NJ, Maltbaek JH, Rossi F, Antonescu CR, Besmer P, DeMatteo RP. Zhang JQ, et al. Among authors: vitiello ga. Oncogene. 2020 Dec;39(49):7153-7165. doi: 10.1038/s41388-020-01489-4. Epub 2020 Oct 6. Oncogene. 2020. PMID: 33024275 Free PMC article.
Oncogenic KIT Modulates Type I IFN-Mediated Antitumor Immunity in GIST.
Liu M, Etherington MS, Hanna A, Medina BD, Vitiello GA, Bowler TG, Param NJ, Levin L, Rossi F, DeMatteo RP. Liu M, et al. Among authors: vitiello ga. Cancer Immunol Res. 2021 May;9(5):542-553. doi: 10.1158/2326-6066.CIR-20-0692. Epub 2021 Mar 1. Cancer Immunol Res. 2021. PMID: 33648985 Free PMC article.
Myosin Light-Chain Kinase Inhibition Potentiates the Antitumor Effects of Avapritinib in PDGFRA D842V-Mutant Gastrointestinal Stromal Tumor.
Rossi F, Liu M, Tieniber A, Etherington MS, Hanna A, Vitiello GA, Param NJ, Do K, Wang L, Antonescu CR, Zeng S, Zhang JQ, DeMatteo RP. Rossi F, et al. Among authors: vitiello ga. Clin Cancer Res. 2023 Jun 1;29(11):2144-2157. doi: 10.1158/1078-0432.CCR-22-0533. Clin Cancer Res. 2023. PMID: 36971786 Free PMC article.
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