Koo EH - Search Results

1

APP upregulation contributes to retinal ganglion cell degeneration via JNK3.

Liu C, Zhang CW, Zhou Y, Wong WQ, Lee LC, Ong WY, Yoon SO, Hong W, Fu XY, Soong TW, Koo EH, Stanton LW, Lim KL, Xiao ZC, Dawe GS. Liu C, et al. Among authors: koo eh. Cell Death Differ. 2018 Mar;25(4):663-678. doi: 10.1038/s41418-017-0005-3. Epub 2017 Dec 13. Cell Death Differ. 2018. PMID: 29238071 Free PMC article.

2

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP.

Nizetic D, Chen CL, Hong W, Koo EH. Nizetic D, et al. Among authors: koo eh. Front Behav Neurosci. 2015 Dec 1;9:299. doi: 10.3389/fnbeh.2015.00299. eCollection 2015. Front Behav Neurosci. 2015. PMID: 26648852 Free PMC article.

3

Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before: ApoE, APP transcription and AD: Hypothesised mechanisms and existing knowledge gaps.

Lee LC, Goh MQL, Koo EH. Lee LC, et al. Among authors: koo eh. Bioessays. 2017 Sep;39(9):10.1002/bies.201700062. doi: 10.1002/bies.201700062. Epub 2017 Jul 21. Bioessays. 2017. PMID: 28731260 Free PMC article. Review.

4

Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer's Disease.

Park G, Nhan HS, Tyan SH, Kawakatsu Y, Zhang C, Navarro M, Koo EH. Park G, et al. Among authors: koo eh. Cell Rep. 2020 Jun 30;31(13):107839. doi: 10.1016/j.celrep.2020.107839. Cell Rep. 2020. PMID: 32610140 Free PMC article.

5

New tricks from an old dog: Another synaptotoxic fragment from APP.

Tyan SH, Koo EH. Tyan SH, et al. Among authors: koo eh. Cell Res. 2015 Nov;25(11):1185-6. doi: 10.1038/cr.2015.125. Epub 2015 Oct 27. Cell Res. 2015. PMID: 26503171 Free PMC article.

6

Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway.

Das U, Wang L, Ganguly A, Saikia JM, Wagner SL, Koo EH, Roy S. Das U, et al. Among authors: koo eh. Nat Neurosci. 2016 Jan;19(1):55-64. doi: 10.1038/nn.4188. Epub 2015 Dec 7. Nat Neurosci. 2016. PMID: 26642089 Free PMC article.

7

Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice.

Park SA, Chevallier N, Tejwani K, Hung MM, Maruyama H, Golde TE, Koo EH. Park SA, et al. Among authors: koo eh. Biochem Biophys Res Commun. 2016 Sep 9;478(1):286-292. doi: 10.1016/j.bbrc.2016.07.015. Epub 2016 Jul 15. Biochem Biophys Res Commun. 2016. PMID: 27425247

8

Enhanced cleavage of APP by co-expressed Bace1 alters the distribution of APP and its fragments in neuronal and non-neuronal cells.

Aow J, Huang TR, Thinakaran G, Koo EH. Aow J, et al. Among authors: koo eh. Mol Neurobiol. 2022 May;59(5):3073-3090. doi: 10.1007/s12035-022-02733-6. Epub 2022 Mar 9. Mol Neurobiol. 2022. PMID: 35266114

9

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.

Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. Baek SH, et al. Among authors: koo eh. Cell. 2002 Jul 12;110(1):55-67. doi: 10.1016/s0092-8674(02)00809-7. Cell. 2002. PMID: 12150997 Free article.

10

A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface.

Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G. Leem JY, et al. Among authors: koo eh. Neurobiol Dis. 2002 Oct;11(1):64-82. doi: 10.1006/nbdi.2002.0546. Neurobiol Dis. 2002. PMID: 12460547

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