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Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.
Umanah GKE, Pignatelli M, Yin X, Chen R, Crawford J, Neifert S, Scarffe L, Behensky AA, Guiberson N, Chang M, Ma E, Kim JW, Castro CC, Mao X, Chen L, Andrabi SA, Pletnikov MV, Pulver AE, Avramopoulos D, Bonci A, Valle D, Dawson TM, Dawson VL. Umanah GKE, et al. Among authors: pignatelli m. Sci Transl Med. 2017 Dec 13;9(420):eaah4985. doi: 10.1126/scitranslmed.aah4985. Sci Transl Med. 2017. PMID: 29237760 Free PMC article.
Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning.
Pignatelli M, Umanah GKE, Ribeiro SP, Chen R, Karuppagounder SS, Yau HJ, Eacker S, Dawson VL, Dawson TM, Bonci A. Pignatelli M, et al. Neuron. 2017 Jan 18;93(2):425-440. doi: 10.1016/j.neuron.2016.12.030. Neuron. 2017. PMID: 28103482 Free article.
Spiraling Connectivity of NAc-VTA Circuitry.
Pignatelli M, Bonci A. Pignatelli M, et al. Neuron. 2018 Jan 17;97(2):261-262. doi: 10.1016/j.neuron.2017.12.046. Neuron. 2018. PMID: 29346748 Free article.
Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons.
Klawonn AM, Fritz M, Castany S, Pignatelli M, Canal C, Similä F, Tejeda HA, Levinsson J, Jaarola M, Jakobsson J, Hidalgo J, Heilig M, Bonci A, Engblom D. Klawonn AM, et al. Among authors: pignatelli m. Immunity. 2021 Feb 9;54(2):225-234.e6. doi: 10.1016/j.immuni.2020.12.016. Epub 2021 Jan 20. Immunity. 2021. PMID: 33476547 Free article.
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior.
Gomez JL, Bonaventura J, Keighron J, Wright KM, Marable DL, Rodriguez LA, Lam S, Carlton ML, Ellis RJ, Jordan CJ, Bi GH, Solis O, Pignatelli M, Bannon MJ, Xi ZX, Tanda G, Michaelides M. Gomez JL, et al. Among authors: pignatelli m. Transl Psychiatry. 2021 Nov 8;11(1):570. doi: 10.1038/s41398-021-01693-0. Transl Psychiatry. 2021. PMID: 34750356 Free PMC article.
Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice.
Pignatelli M, Tejeda HA, Barker DJ, Bontempi L, Wu J, Lopez A, Palma Ribeiro S, Lucantonio F, Parise EM, Torres-Berrio A, Alvarez-Bagnarol Y, Marino RAM, Cai ZL, Xue M, Morales M, Tamminga CA, Nestler EJ, Bonci A. Pignatelli M, et al. Mol Psychiatry. 2021 Jun;26(6):1860-1879. doi: 10.1038/s41380-020-0686-8. Epub 2020 Mar 11. Mol Psychiatry. 2021. PMID: 32161361 Free PMC article.
290 results