Lomas DA - Search Results

1

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Partridge FA, Brown AE, Buckingham SD, Willis NJ, Wynne GM, Forman R, Else KJ, Morrison AA, Matthews JB, Russell AJ, Lomas DA, Sattelle DB. Partridge FA, et al. Among authors: lomas da. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):8-21. doi: 10.1016/j.ijpddr.2017.11.004. Epub 2017 Dec 2. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29223747 Free PMC article.

2

C. elegans expressing D76N β₂-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis.

Faravelli G, Raimondi S, Marchese L, Partridge FA, Soria C, Mangione PP, Canetti D, Perni M, Aprile FA, Zorzoli I, Di Schiavi E, Lomas DA, Bellotti V, Sattelle DB, Giorgetti S. Faravelli G, et al. Among authors: lomas da. Sci Rep. 2019 Dec 27;9(1):19960. doi: 10.1038/s41598-019-56498-5. Sci Rep. 2019. PMID: 31882874 Free PMC article.

3

Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.

Malintan NT, Buckingham SD, Lomas DA, Sattelle DB. Malintan NT, et al. Among authors: lomas da. Sci Rep. 2019 Nov 21;9(1):17293. doi: 10.1038/s41598-019-53535-1. Sci Rep. 2019. PMID: 31754242 Free PMC article.

4

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.

Khabirova E, Moloney A, Marciniak SJ, Williams J, Lomas DA, Oliver SG, Favrin G, Sattelle DB, Crowther DC. Khabirova E, et al. Among authors: lomas da. PLoS One. 2014 Jul 31;9(7):e102985. doi: 10.1371/journal.pone.0102985. eCollection 2014. PLoS One. 2014. PMID: 25080104 Free PMC article.

5

Alzheimer's disease: insights from Drosophila melanogaster models.

Moloney A, Sattelle DB, Lomas DA, Crowther DC. Moloney A, et al. Among authors: lomas da. Trends Biochem Sci. 2010 Apr;35(4):228-35. doi: 10.1016/j.tibs.2009.11.004. Epub 2009 Dec 25. Trends Biochem Sci. 2010. PMID: 20036556 Free PMC article. Review.

6

The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster.

Kohlhoff KJ, Jahn TR, Lomas DA, Dobson CM, Crowther DC, Vendruscolo M. Kohlhoff KJ, et al. Among authors: lomas da. Integr Biol (Camb). 2011 Jul;3(7):755-60. doi: 10.1039/c0ib00149j. Epub 2011 Jun 23. Integr Biol (Camb). 2011. PMID: 21698336 Free PMC article.

7

Alpha1-antitrypsin deficiency and autophagy.

Marciniak SJ, Lomas DA. Marciniak SJ, et al. Among authors: lomas da. N Engl J Med. 2010 Nov 4;363(19):1863-4. doi: 10.1056/NEJMcibr1008007. N Engl J Med. 2010. PMID: 21047232 No abstract available.

8

Genetic susceptibility.

Marciniak SJ, Lomas DA. Marciniak SJ, et al. Among authors: lomas da. Clin Chest Med. 2014 Mar;35(1):29-38. doi: 10.1016/j.ccm.2013.10.008. Epub 2013 Dec 12. Clin Chest Med. 2014. PMID: 24507835 Free article. Review.

9

Therapeutic targets from a Drosophila model of Alzheimer's disease.

Crowther DC, Kinghorn KJ, Page R, Lomas DA. Crowther DC, et al. Among authors: lomas da. Curr Opin Pharmacol. 2004 Oct;4(5):513-6. doi: 10.1016/j.coph.2004.07.001. Curr Opin Pharmacol. 2004. PMID: 15351357 Review.

10

A Drosophila model of Alzheimer's disease.

Crowther DC, Page R, Chandraratna D, Lomas DA. Crowther DC, et al. Among authors: lomas da. Methods Enzymol. 2006;412:234-55. doi: 10.1016/S0076-6879(06)12015-7. Methods Enzymol. 2006. PMID: 17046662

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