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Page 1
Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Flannery PC, DeSisto JA, Amani V, Venkataraman S, Lemma RT, Prince EW, Donson A, Moroze EE, Hoffman L, Levy JMM, Foreman N, Vibhakar R, Green AL. Flannery PC, et al. Among authors: lemma rt. Oncol Rep. 2018 Feb;39(2):455-464. doi: 10.3892/or.2017.6122. Epub 2017 Nov 29. Oncol Rep. 2018. PMID: 29207163 Free PMC article.
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Balakrishnan I, Danis E, Pierce A, Madhavan K, Wang D, Dahl N, Sanford B, Birks DK, Davidson N, Metselaar DS, Meel MH, Lemma R, Donson A, Vijmasi T, Katagi H, Sola I, Fosmire S, Alimova I, Steiner J, Gilani A, Hulleman E, Serkova NJ, Hashizume R, Hawkins C, Carcaboso AM, Gupta N, Monje M, Jabado N, Jones K, Foreman N, Green A, Vibhakar R, Venkataraman S. Balakrishnan I, et al. Cell Rep. 2020 Oct 20;33(3):108286. doi: 10.1016/j.celrep.2020.108286. Cell Rep. 2020. PMID: 33086074 Free PMC article.
Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma.
DeSisto JA, Flannery P, Lemma R, Pathak A, Mestnik S, Philips N, Bales NJ, Kashyap T, Moroze E, Venkataraman S, Kung AL, Carter BD, Landesman Y, Vibhakar R, Green AL. DeSisto JA, et al. Mol Cancer Ther. 2020 Feb;19(2):540-551. doi: 10.1158/1535-7163.MCT-18-1319. Epub 2019 Oct 8. Mol Cancer Ther. 2020. PMID: 31594826 Free PMC article.
BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.
Green AL, DeSisto J, Flannery P, Lemma R, Knox A, Lemieux M, Sanford B, O'Rourke R, Ramkissoon S, Jones K, Perry J, Hui X, Moroze E, Balakrishnan I, O'Neill AF, Dunn K, DeRyckere D, Danis E, Safadi A, Gilani A, Hubbell-Engler B, Nuss Z, Levy JMM, Serkova N, Venkataraman S, Graham DK, Foreman N, Ligon K, Jones K, Kung AL, Vibhakar R. Green AL, et al. Oncogene. 2020 Mar;39(11):2305-2327. doi: 10.1038/s41388-019-1125-7. Epub 2019 Dec 16. Oncogene. 2020. PMID: 31844250 Free PMC article.
Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine.
Green AL, Flannery P, Hankinson TC, O'Neill B, Amani V, DeSisto J, Knox A, Chatwin H, Lemma R, Hoffman LM, Mulcahy Levy J, Raybin J, Hemenway M, Gilani A, Koschmann C, Dahl N, Handler M, Pierce A, Venkataraman S, Foreman N, Vibhakar R, Wempe MF, Dorris K. Green AL, et al. Neurooncol Adv. 2020 Feb 24;2(1):vdaa021. doi: 10.1093/noajnl/vdaa021. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642682 Free PMC article.
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
DeSisto J, Lucas JT Jr, Xu K, Donson A, Lin T, Sanford B, Wu G, Tran QT, Hedges D, Hsu CY, Armstrong GT, Arnold M, Bhatia S, Flannery P, Lemma R, Hardie L, Schüller U, Venkataraman S, Hoffman LM, Dorris K, Mulcahy Levy JM, Hankinson TC, Handler M, Liu AK, Foreman N, Vibhakar R, Jones K, Allen S, Zhang J, Baker SJ, Merchant TE, Orr BA, Green AL. DeSisto J, et al. Nat Commun. 2021 Sep 20;12(1):5531. doi: 10.1038/s41467-021-25709-x. Nat Commun. 2021. PMID: 34545084 Free PMC article.
Correction: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.
Green AL, DeSisto J, Flannery P, Lemma R, Knox A, Lemieux M, Sanford B, O'Rourke R, Ramkissoon S, Jones K, Perry J, Hui X, Moroze E, Balakrishnan I, O'Neill AF, Dunn K, DeRyckere D, Danis E, Safadi A, Gilani A, Hubbell-Engler B, Nuss Z, Levy JMM, Serkova N, Venkataraman S, Graham DK, Foreman N, Ligon K, Jones K, Kung AL, Vibhakar R. Green AL, et al. Oncogene. 2020 Mar;39(12):2641. doi: 10.1038/s41388-020-1155-1. Oncogene. 2020. PMID: 31969682