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MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9.
Vychytilova-Faltejskova P, Merhautova J, Machackova T, Gutierrez-Garcia I, Garcia-Solano J, Radova L, Brchnelova D, Slaba K, Svoboda M, Halamkova J, Demlova R, Kiss I, Vyzula R, Conesa-Zamora P, Slaby O. Vychytilova-Faltejskova P, et al. Oncogenesis. 2017 Dec 4;6(11):399. doi: 10.1038/s41389-017-0006-6. Oncogenesis. 2017. PMID: 29199273 Free PMC article.
Colorectal serrated adenocarcinoma shows a different profile of oncogene mutations, MSI status and DNA repair protein expression compared to conventional and sporadic MSI-H carcinomas.
García-Solano J, Conesa-Zamora P, Carbonell P, Trujillo-Santos J, Torres-Moreno D D, Pagán-Gómez I, Rodríguez-Braun E, Pérez-Guillermo M. García-Solano J, et al. Int J Cancer. 2012 Oct 15;131(8):1790-9. doi: 10.1002/ijc.27454. Epub 2012 Mar 14. Int J Cancer. 2012. PMID: 22287190
Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma.
Conesa-Zamora P, García-Solano J, García-García F, Turpin Mdel C, Trujillo-Santos J, Torres-Moreno D, Oviedo-Ramírez I, Carbonell-Muñoz R, Muñoz-Delgado E, Rodriguez-Braun E, Conesa A, Pérez-Guillermo M. Conesa-Zamora P, et al. Int J Cancer. 2013 Jan 15;132(2):297-307. doi: 10.1002/ijc.27674. Epub 2012 Jun 28. Int J Cancer. 2013. PMID: 22696308
Methylome profiling reveals functions and genes which are differentially methylated in serrated compared to conventional colorectal carcinoma.
Conesa-Zamora P, García-Solano J, Turpin Mdel C, Sebastián-León P, Torres-Moreno D, Estrada E, Tuomisto A, Wilce J, Mäkinen MJ, Pérez-Guillermo M, Conesa A. Conesa-Zamora P, et al. Clin Epigenetics. 2015 Sep 17;7(1):101. doi: 10.1186/s13148-015-0128-7. eCollection 2015. Clin Epigenetics. 2015. PMID: 26388956 Free PMC article.
80 results