Yang H - Search Results

1

CRISPR/Cas9-mediated targeted chromosome elimination.

Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Among authors: yang h. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.

2

Highly efficient base editing in human tripronuclear zygotes.

Zhou C, Zhang M, Wei Y, Sun Y, Sun Y, Pan H, Yao N, Zhong W, Li Y, Li W, Yang H, Chen ZJ. Zhou C, et al. Among authors: yang h. Protein Cell. 2017 Oct;8(10):772-775. doi: 10.1007/s13238-017-0459-6. Protein Cell. 2017. PMID: 28875305 Free PMC article. No abstract available.

3

Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing.

Yao X, Liu Z, Wang X, Wang Y, Nie YH, Lai L, Sun R, Shi L, Sun Q, Yang H. Yao X, et al. Among authors: yang h. Cell Res. 2018 Mar;28(3):379-382. doi: 10.1038/cr.2018.9. Epub 2018 Jan 12. Cell Res. 2018. PMID: 29327726 Free PMC article. No abstract available.

4

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.

Zhou H, Liu J, Zhou C, Gao N, Rao Z, Li H, Hu X, Li C, Yao X, Shen X, Sun Y, Wei Y, Liu F, Ying W, Zhang J, Tang C, Zhang X, Xu H, Shi L, Cheng L, Huang P, Yang H. Zhou H, et al. Among authors: yang h. Nat Neurosci. 2018 Mar;21(3):440-446. doi: 10.1038/s41593-017-0060-6. Epub 2018 Jan 15. Nat Neurosci. 2018. PMID: 29335603

5

CRISPR/Cas9-mediated Targeted Integration In Vivo Using a Homology-mediated End Joining-based Strategy.

Yao X, Wang X, Liu J, Shi L, Huang P, Yang H. Yao X, et al. Among authors: yang h. J Vis Exp. 2018 Mar 12;(133):56844. doi: 10.3791/56844. J Vis Exp. 2018. PMID: 29578506 Free PMC article.

6

Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells.

Yao X, Zhang M, Wang X, Ying W, Hu X, Dai P, Meng F, Shi L, Sun Y, Yao N, Zhong W, Li Y, Wu K, Li W, Chen ZJ, Yang H. Yao X, et al. Among authors: yang h. Dev Cell. 2018 May 21;45(4):526-536.e5. doi: 10.1016/j.devcel.2018.04.021. Dev Cell. 2018. PMID: 29787711 Free article.

7

Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing.

Zhang H, Pan H, Zhou C, Wei Y, Ying W, Li S, Wang G, Li C, Ren Y, Li G, Ding X, Sun Y, Li GL, Song L, Li Y, Yang H, Liu Z. Zhang H, et al. Among authors: yang h. Development. 2018 Oct 17;145(20):dev168906. doi: 10.1242/dev.168906. Development. 2018. PMID: 30275281

8

Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.

Yang G, Zhou C, Wang R, Huang S, Wei Y, Yang X, Liu Y, Li J, Lu Z, Ying W, Li X, Jing N, Huang X, Yang H, Qiao Y. Yang G, et al. Among authors: yang x, yang h. Cell Rep. 2019 Jan 8;26(2):302-312.e4. doi: 10.1016/j.celrep.2018.12.046. Cell Rep. 2019. PMID: 30625312 Free article.

9

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. Zuo E, et al. Among authors: yang h. Science. 2019 Apr 19;364(6437):289-292. doi: 10.1126/science.aav9973. Epub 2019 Feb 28. Science. 2019. PMID: 30819928 Free PMC article.

10

Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors.

Zhang M, Zhou C, Wei Y, Xu C, Pan H, Ying W, Sun Y, Sun Y, Xiao Q, Yao N, Zhong W, Li Y, Wu K, Yuan G, Mitalipov S, Chen ZJ, Yang H. Zhang M, et al. Among authors: yang h. Genome Biol. 2019 May 22;20(1):101. doi: 10.1186/s13059-019-1703-6. Genome Biol. 2019. PMID: 31118069 Free PMC article.

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