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Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, Yusa K, Linnarsson S, Graf T, Parmar M, Kaji K. Ruetz T, et al. Among authors: parmar m. Cell Stem Cell. 2017 Dec 7;21(6):791-805.e9. doi: 10.1016/j.stem.2017.10.013. Epub 2017 Nov 22. Cell Stem Cell. 2017. PMID: 29174331 Free PMC article.
Direct conversion of human fibroblasts to dopaminergic neurons.
Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M. Pfisterer U, et al. Among authors: parmar m. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10343-8. doi: 10.1073/pnas.1105135108. Epub 2011 Jun 6. Proc Natl Acad Sci U S A. 2011. PMID: 21646515 Free PMC article.
Efficient induction of functional neurons from adult human fibroblasts.
Pfisterer U, Wood J, Nihlberg K, Hallgren O, Bjermer L, Westergren-Thorsson G, Lindvall O, Parmar M. Pfisterer U, et al. Among authors: parmar m. Cell Cycle. 2011 Oct 1;10(19):3311-6. doi: 10.4161/cc.10.19.17584. Epub 2011 Oct 1. Cell Cycle. 2011. PMID: 21934358
Generation of induced neurons via direct conversion in vivo.
Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M. Torper O, et al. Among authors: parmar m. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):7038-43. doi: 10.1073/pnas.1303829110. Epub 2013 Mar 25. Proc Natl Acad Sci U S A. 2013. PMID: 23530235 Free PMC article.
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons.
Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. Iovino M, et al. Among authors: parmar m. Acta Neuropathol. 2014 Feb;127(2):283-95. doi: 10.1007/s00401-013-1219-1. Epub 2013 Nov 30. Acta Neuropathol. 2014. PMID: 24292008 Free PMC article.
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Grealish S, et al. Among authors: parmar m. Cell Stem Cell. 2014 Nov 6;15(5):653-65. doi: 10.1016/j.stem.2014.09.017. Epub 2014 Nov 6. Cell Stem Cell. 2014. PMID: 25517469 Free PMC article.
1,025 results