Kosma P - Search Results

1

Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.

Pantophlet R, Trattnig N, Murrell S, Lu N, Chau D, Rempel C, Wilson IA, Kosma P. Pantophlet R, et al. Among authors: kosma p. Nat Commun. 2017 Nov 17;8(1):1601. doi: 10.1038/s41467-017-01640-y. Nat Commun. 2017. PMID: 29150603 Free PMC article.

2

Synthesis of an Undecasaccharide Featuring an Oligomannosidic Heptasaccharide and a Bacterial Kdo-lipid A Backbone for Eliciting Neutralizing Antibodies to Mammalian Oligomannose on the HIV-1 Envelope Spike.

Trattnig N, Blaukopf M, Bruxelle JF, Pantophlet R, Kosma P. Trattnig N, et al. Among authors: kosma p. J Am Chem Soc. 2019 May 15;141(19):7946-7954. doi: 10.1021/jacs.9b02872. Epub 2019 Apr 30. J Am Chem Soc. 2019. PMID: 31010286 Free PMC article.

3

Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies.

Bruxelle JF, Kirilenko T, Qureshi Q, Lu N, Trattnig N, Kosma P, Pantophlet R. Bruxelle JF, et al. Among authors: kosma p. Sci Rep. 2020 May 5;10(1):7582. doi: 10.1038/s41598-020-64500-8. Sci Rep. 2020. PMID: 32371950 Free PMC article.

4

A glycoside analog of mammalian oligomannose formulated with a TLR4-stimulating adjuvant elicits HIV-1 cross-reactive antibodies.

Bruxelle JF, Kirilenko T, Trattnig N, Yang Y, Cattin M, Kosma P, Pantophlet R. Bruxelle JF, et al. Among authors: kosma p. Sci Rep. 2021 Feb 25;11(1):4637. doi: 10.1038/s41598-021-84116-w. Sci Rep. 2021. PMID: 33633304 Free PMC article.

5

Synthesis of a Pentasaccharide Fragment Related to the Inner Core Region of Rhizobial and Agrobacterial Lipopolysaccharides.

Trattnig N, Farcet JB, Gritsch P, Christler A, Pantophlet R, Kosma P. Trattnig N, et al. Among authors: kosma p. J Org Chem. 2017 Dec 1;82(23):12346-12358. doi: 10.1021/acs.joc.7b02172. Epub 2017 Oct 26. J Org Chem. 2017. PMID: 29028168 Free PMC article.

6

Comparative Antigenicity of Thiourea and Adipic Amide Linked Neoglycoconjugates Containing Modified Oligomannose Epitopes for the Carbohydrate-Specific anti-HIV Antibody 2G12.

Trattnig N, Mayrhofer P, Kunert R, Mach L, Pantophlet R, Kosma P. Trattnig N, et al. Among authors: kosma p. Bioconjug Chem. 2019 Jan 16;30(1):70-82. doi: 10.1021/acs.bioconjchem.8b00731. Epub 2018 Dec 28. Bioconjug Chem. 2019. PMID: 30525492 Free PMC article.

7

Synthetic Neoglycoconjugates of Hepta- and Nonamannoside Ligands for Eliciting Oligomannose-Specific HIV-1-Neutralizing Antibodies.

Cattin M, Bruxelle JF, Ng K, Blaukopf M, Pantophlet R, Kosma P. Cattin M, et al. Among authors: kosma p. Chembiochem. 2022 Apr 5;23(7):e202200061. doi: 10.1002/cbic.202200061. Epub 2022 Feb 11. Chembiochem. 2022. PMID: 35104013 Free PMC article.

8

Site-Specific Multi-Functionalization of the Carrier Protein CRM₁₉₇ by Disulfide Rebridging for Conjugate Vaccine Development.

Trattnig N, Li Z, Bosman GP, Kosma P, Boons GJ. Trattnig N, et al. Among authors: kosma p. Chembiochem. 2022 Nov 4;23(21):e202200408. doi: 10.1002/cbic.202200408. Epub 2022 Sep 29. Chembiochem. 2022. PMID: 36098623 Free PMC article.

9

Rhamnogalacturonan II: Chemical Synthesis of a Substructure Including α-2,3-Linked Kdo*.

Mancuso E, Romanò C, Trattnig N, Gritsch P, Kosma P, Clausen MH. Mancuso E, et al. Among authors: kosma p. Chemistry. 2021 Apr 26;27(24):7099-7102. doi: 10.1002/chem.202100837. Epub 2021 Apr 9. Chemistry. 2021. PMID: 33769639

10

Conformationally constrained lipid A mimetics for exploration of structural basis of TLR4/MD-2 activation by lipopolysaccharide.

Artner D, Oblak A, Ittig S, Garate JA, Horvat S, Arrieumerlou C, Hofinger A, Oostenbrink C, Jerala R, Kosma P, Zamyatina A. Artner D, et al. Among authors: kosma p. ACS Chem Biol. 2013 Nov 15;8(11):2423-32. doi: 10.1021/cb4003199. Epub 2013 Sep 26. ACS Chem Biol. 2013. PMID: 23952219 Free PMC article.

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