Sundaramoorthy R - Search Results

1

The Ndc80 complex targets Bod1 to human mitotic kinetochores.

Schleicher K, Porter M, Ten Have S, Sundaramoorthy R, Porter IM, Swedlow JR. Schleicher K, et al. Among authors: sundaramoorthy r. Open Biol. 2017 Nov;7(11):170099. doi: 10.1098/rsob.170099. Open Biol. 2017. PMID: 29142109 Free PMC article.

2

Structure of Staphylococcus aureus EsxA suggests a contribution to virulence by action as a transport chaperone and/or adaptor protein.

Sundaramoorthy R, Fyfe PK, Hunter WN. Sundaramoorthy R, et al. J Mol Biol. 2008 Nov 14;383(3):603-14. doi: 10.1016/j.jmb.2008.08.047. Epub 2008 Aug 27. J Mol Biol. 2008. PMID: 18773907 Free PMC article.

3

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3-H4 tetramers and Asf1-H3-H4 complexes.

Hammond CM, Sundaramoorthy R, Larance M, Lamond A, Stevens MA, El-Mkami H, Norman DG, Owen-Hughes T. Hammond CM, et al. Among authors: sundaramoorthy r. Nucleic Acids Res. 2016 Jul 27;44(13):6157-72. doi: 10.1093/nar/gkw209. Epub 2016 Apr 1. Nucleic Acids Res. 2016. PMID: 27036862 Free PMC article.

4

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

Kumar A, Chaugule VK, Condos TEC, Barber KR, Johnson C, Toth R, Sundaramoorthy R, Knebel A, Shaw GS, Walden H. Kumar A, et al. Among authors: sundaramoorthy r. Nat Struct Mol Biol. 2017 May;24(5):475-483. doi: 10.1038/nsmb.3400. Epub 2017 Apr 17. Nat Struct Mol Biol. 2017. PMID: 28414322 Free PMC article.

5

The crystal structure of a plant 3-ketoacyl-CoA thiolase reveals the potential for redox control of peroxisomal fatty acid beta-oxidation.

Sundaramoorthy R, Micossi E, Alphey MS, Germain V, Bryce JH, Smith SM, Leonard GA, Hunter WN. Sundaramoorthy R, et al. J Mol Biol. 2006 Jun 2;359(2):347-57. doi: 10.1016/j.jmb.2006.03.032. Epub 2006 Mar 29. J Mol Biol. 2006. PMID: 16630629

6

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.

Kumar A, Aguirre JD, Condos TE, Martinez-Torres RJ, Chaugule VK, Toth R, Sundaramoorthy R, Mercier P, Knebel A, Spratt DE, Barber KR, Shaw GS, Walden H. Kumar A, et al. Among authors: sundaramoorthy r. EMBO J. 2015 Oct 14;34(20):2506-21. doi: 10.15252/embj.201592337. Epub 2015 Aug 7. EMBO J. 2015. PMID: 26254304 Free PMC article.

7

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Böttcher B, Norman DG, Owen-Hughes T. Sundaramoorthy R, et al. Elife. 2017 Mar 23;6:e22510. doi: 10.7554/eLife.22510. Elife. 2017. PMID: 28332978 Free PMC article.

8

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, Mabbitt PD, Sundaramoorthy R, Hofmann K, van Aalten DMF, Virdee S. Pao KC, et al. Among authors: sundaramoorthy r. Nature. 2018 Apr;556(7701):381-385. doi: 10.1038/s41586-018-0026-1. Epub 2018 Apr 11. Nature. 2018. PMID: 29643511 Free article.

9

Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription.

Blümli S, Wiechens N, Wu MY, Singh V, Gierlinski M, Schweikert G, Gilbert N, Naughton C, Sundaramoorthy R, Varghese J, Gourlay R, Soares R, Clark D, Owen-Hughes T. Blümli S, et al. Among authors: sundaramoorthy r. Cell Rep. 2021 Nov 2;37(5):109943. doi: 10.1016/j.celrep.2021.109943. Cell Rep. 2021. PMID: 34731603 Free PMC article.

10

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains.

Ryan DP, Sundaramoorthy R, Martin D, Singh V, Owen-Hughes T. Ryan DP, et al. Among authors: sundaramoorthy r. EMBO J. 2011 May 27;30(13):2596-609. doi: 10.1038/emboj.2011.166. EMBO J. 2011. PMID: 21623345 Free PMC article.

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