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Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases.
Gregorczyk M, Pastore G, Muñoz I, Carroll T, Streubel J, Munro M, Lis P, Lange S, Lamoliatte F, Macartney T, Toth R, Brown F, Hastie J, Pereira G, Durocher D, Rouse J. Gregorczyk M, et al. Among authors: brown f. Life Sci Alliance. 2023 May 15;6(7):e202201740. doi: 10.26508/lsa.202201740. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37188479 Free PMC article.
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural… See abstract for full author list ➔ Gordon DE, et al. Among authors: brown f. Science. 2020 Dec 4;370(6521):eabe9403. doi: 10.1126/science.abe9403. Epub 2020 Oct 15. Science. 2020. PMID: 33060197 Free PMC article.
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.
Rihn SJ, Merits A, Bakshi S, Turnbull ML, Wickenhagen A, Alexander AJT, Baillie C, Brennan B, Brown F, Brunker K, Bryden SR, Burness KA, Carmichael S, Cole SJ, Cowton VM, Davies P, Davis C, De Lorenzo G, Donald CL, Dorward M, Dunlop JI, Elliott M, Fares M, da Silva Filipe A, Freitas JR, Furnon W, Gestuveo RJ, Geyer A, Giesel D, Goldfarb DM, Goodman N, Gunson R, Hastie CJ, Herder V, Hughes J, Johnson C, Johnson N, Kohl A, Kerr K, Leech H, Lello LS, Li K, Lieber G, Liu X, Lingala R, Loney C, Mair D, McElwee MJ, McFarlane S, Nichols J, Nomikou K, Orr A, Orton RJ, Palmarini M, Parr YA, Pinto RM, Raggett S, Reid E, Robertson DL, Royle J, Cameron-Ruiz N, Shepherd JG, Smollett K, Stewart DG, Stewart M, Sugrue E, Szemiel AM, Taggart A, Thomson EC, Tong L, Torrie LS, Toth R, Varjak M, Wang S, Wilkinson SG, Wyatt PG, Zusinaite E, Alessi DR, Patel AH, Zaid A, Wilson SJ, Mahalingam S. Rihn SJ, et al. Among authors: brown f. PLoS Biol. 2021 Feb 25;19(2):e3001091. doi: 10.1371/journal.pbio.3001091. eCollection 2021 Feb. PLoS Biol. 2021. PMID: 33630831 Free PMC article.
Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators.
Jadav R, Weiland F, Noordermeer SM, Carroll T, Gao Y, Wang J, Zhou H, Lamoliatte F, Toth R, Macartney T, Brown F, Hastie CJ, Alabert C, van Attikum H, Zenke F, Masson JY, Rouse J. Jadav R, et al. Among authors: brown f. Mol Cell Proteomics. 2024 Aug;23(8):100802. doi: 10.1016/j.mcpro.2024.100802. Epub 2024 Jun 15. Mol Cell Proteomics. 2024. PMID: 38880245 Free PMC article.
Downhill running does not alter blood C1q availability or complement-dependent cytotoxicity of therapeutic monoclonal antibodies against haematological cancer cell lines in vitro.
Collier-Bain HD, Brown FF, Causer AJ, Ross L, Rothschild-Rodriguez D, Browne N, Eddy R, Cleary KL, Gray JC, Cragg MS, Moore S, Murray J, Turner JE, Campbell JP. Collier-Bain HD, et al. Among authors: brown ff. Sci Rep. 2024 Nov 15;14(1):28239. doi: 10.1038/s41598-024-79690-8. Sci Rep. 2024. PMID: 39548231 Free PMC article.
Characterising how a single bout of exercise in people with myeloma affects clonal plasma cell and immune effector cell frequency in blood, and daratumumab efficacy in vitro.
Collier-Bain HD, Emery A, Brown FF, Causer AJ, Oliver R, Eddy R, Leach S, Graby J, Augustine D, Moore S, Crowe J, Murray J, Turner JE, Campbell JP. Collier-Bain HD, et al. Among authors: brown ff. Brain Behav Immun Health. 2024 Sep 19;42:100865. doi: 10.1016/j.bbih.2024.100865. eCollection 2024 Dec. Brain Behav Immun Health. 2024. PMID: 39411424 Free PMC article.
Acquired BCL2 variants associated with venetoclax resistance in acute myeloid leukemia.
Brown FC, Wang X, Birkinshaw RW, Chua CC, Morley TD, Kasapgil S, Pomilio G, Blombery P, Huang DCS Professor, Czabotar PE, Priore SF, Yang G, Carroll MP, Wei AH, Perl AE. Brown FC, et al. Blood Adv. 2024 Oct 7:bloodadvances.2024014446. doi: 10.1182/bloodadvances.2024014446. Online ahead of print. Blood Adv. 2024. PMID: 39374584
1,796 results