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Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.
Unsworth AJ, Bye AP, Sage T, Gaspar RS, Eaton N, Drew C, Stainer A, Kriek N, Volberding PJ, Hutchinson JL, Riley R, Jones S, Mundell SJ, Cui W, Falet H, Gibbins JM. Unsworth AJ, et al. Among authors: hutchinson jl. Haematologica. 2021 Jul 1;106(7):1968-1978. doi: 10.3324/haematol.2019.223529. Haematologica. 2021. PMID: 32467143 Free PMC article.
Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial.
Johnson TW, Baos S, Collett L, Hutchinson JL, Nkau M, Molina M, Aungraheeta R, Reilly-Stitt C, Bowles R, Reeves BC, Rogers CA, Mundell SJ, Baumbach A, Mumford AD. Johnson TW, et al. Among authors: hutchinson jl. J Am Heart Assoc. 2020 Dec 15;9(24):e016495. doi: 10.1161/JAHA.120.016495. Epub 2020 Dec 11. J Am Heart Assoc. 2020. PMID: 33305660 Free PMC article. Clinical Trial.
Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling.
Zhao X, Alibhai D, Sun T, Khalil J, Hutchinson JL, Olzak K, Williams CM, Li Y, Sessions R, Cross S, Seager R, Aungraheeta R, Leard A, McKinnon CM, Phillips D, Zhang L, Poole AW, Banting G, Mundell SJ. Zhao X, et al. Among authors: hutchinson jl. Blood Adv. 2021 Apr 13;5(7):1884-1898. doi: 10.1182/bloodadvances.2020003182. Blood Adv. 2021. PMID: 33792632 Free PMC article.
30 results