Zhao Y - Search Results

1

Fluoxetine induces autophagic cell death via eEF2K-AMPK-mTOR-ULK complex axis in triple negative breast cancer.

Sun D, Zhu L, Zhao Y, Jiang Y, Chen L, Yu Y, Ouyang L. Sun D, et al. Among authors: zhao y. Cell Prolif. 2018 Apr;51(2):e12402. doi: 10.1111/cpr.12402. Epub 2017 Nov 1. Cell Prolif. 2018. PMID: 29094413 Free PMC article.

2

Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer.

Zhao YQ, Yin YQ, Liu J, Wang GH, Huang J, Zhu LJ, Wang JH. Zhao YQ, et al. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50. doi: 10.1038/aps.2016.60. Epub 2016 Jul 11. Acta Pharmacol Sin. 2016. PMID: 27397540 Free PMC article.

3

Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer.

Yao D, Zhou Y, Zhu L, Ouyang L, Zhang J, Jiang Y, Zhao Y, Sun D, Yang S, Yu Y, Wang J. Yao D, et al. Among authors: zhao y. Eur J Med Chem. 2017 Nov 10;140:155-171. doi: 10.1016/j.ejmech.2017.08.067. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28923383

4

Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer.

Guo Y, Zhao Y, Wang G, Chen Y, Jiang Y, Ouyang L, Liu B. Guo Y, et al. Among authors: zhao y. Eur J Med Chem. 2018 Jan 1;143:402-418. doi: 10.1016/j.ejmech.2017.11.065. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29202403

5

Deconvoluting the complexity of microRNAs in autophagy to improve potential cancer therapy.

Yao D, Jiang Y, Gao S, Shang L, Zhao Y, Huang J, Wang J, Yang S, Chen L. Yao D, et al. Among authors: zhao y. Cell Prolif. 2016 Oct;49(5):541-53. doi: 10.1111/cpr.12277. Epub 2016 Jul 20. Cell Prolif. 2016. PMID: 27436709 Free PMC article. Review.

6

A natural product from Cannabis sativa subsp. sativa inhibits homeodomain-interacting protein kinase 2 (HIPK2), attenuating MPP⁺-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Wang G, Zhu L, Zhao Y, Gao S, Sun D, Yuan J, Huang Y, Zhang X, Yao X. Wang G, et al. Among authors: zhao y. Bioorg Chem. 2017 Jun;72:64-73. doi: 10.1016/j.bioorg.2017.03.011. Epub 2017 Mar 30. Bioorg Chem. 2017. PMID: 28366826

7

Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.

Ouyang L, Zhang L, Liu J, Fu L, Yao D, Zhao Y, Zhang S, Wang G, He G, Liu B. Ouyang L, et al. Among authors: zhao y. J Med Chem. 2017 Dec 28;60(24):9990-10012. doi: 10.1021/acs.jmedchem.7b00275. Epub 2017 Dec 7. J Med Chem. 2017. PMID: 29172540

8

Dual-target kinase drug design: Current strategies and future directions in cancer therapy.

Sun D, Zhao Y, Zhang S, Zhang L, Liu B, Ouyang L. Sun D, et al. Among authors: zhao y. Eur J Med Chem. 2020 Feb 15;188:112025. doi: 10.1016/j.ejmech.2019.112025. Epub 2020 Jan 2. Eur J Med Chem. 2020. PMID: 31931340 Review.

9

Discovery of a Novel Dual-Target Inhibitor of ERK1 and ERK5 That Induces Regulated Cell Death to Overcome Compensatory Mechanism in Specific Tumor Types.

Wang G, Zhao Y, Liu Y, Sun D, Zhen Y, Liu J, Fu L, Zhang L, Ouyang L. Wang G, et al. Among authors: zhao y. J Med Chem. 2020 Apr 23;63(8):3976-3995. doi: 10.1021/acs.jmedchem.9b01896. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32078308

10

Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.

Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X. Zhao Y, et al. Biomed Pharmacother. 2020 Oct;130:110522. doi: 10.1016/j.biopha.2020.110522. Epub 2020 Jul 28. Biomed Pharmacother. 2020. PMID: 32736236 Free article.

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