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Page 1
Novel Toxoplasma gondii inhibitor chemotypes.
Sanford AG, Schulze TT, Potluri LP, Hemsley RM, Larson JJ, Judge AK, Zach SJ, Wang X, Charman SA, Vennerstrom JL, Davis PH. Sanford AG, et al. Among authors: vennerstrom jl. Parasitol Int. 2018 Apr;67(2):107-111. doi: 10.1016/j.parint.2017.10.010. Epub 2018 Jan 4. Parasitol Int. 2018. PMID: 29081387 Free PMC article.
Identification of an antimalarial synthetic trioxolane drug development candidate.
Vennerstrom JL, Arbe-Barnes S, Brun R, Charman SA, Chiu FC, Chollet J, Dong Y, Dorn A, Hunziker D, Matile H, McIntosh K, Padmanilayam M, Santo Tomas J, Scheurer C, Scorneaux B, Tang Y, Urwyler H, Wittlin S, Charman WN. Vennerstrom JL, et al. Nature. 2004 Aug 19;430(7002):900-4. doi: 10.1038/nature02779. Nature. 2004. PMID: 15318224 Free article.
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.
Dong Y, Chollet J, Matile H, Charman SA, Chiu FC, Charman WN, Scorneaux B, Urwyler H, Santo Tomas J, Scheurer C, Snyder C, Dorn A, Wang X, Karle JM, Tang Y, Wittlin S, Brun R, Vennerstrom JL. Dong Y, et al. Among authors: vennerstrom jl. J Med Chem. 2005 Jul 28;48(15):4953-61. doi: 10.1021/jm049040u. J Med Chem. 2005. PMID: 16033274
Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes.
Dong Y, Tang Y, Chollet J, Matile H, Wittlin S, Charman SA, Charman WN, Tomas JS, Scheurer C, Snyder C, Scorneaux B, Bajpai S, Alexander SA, Wang X, Padmanilayam M, Cheruku SR, Brun R, Vennerstrom JL. Dong Y, et al. Among authors: vennerstrom jl. Bioorg Med Chem. 2006 Sep 15;14(18):6368-82. doi: 10.1016/j.bmc.2006.05.041. Epub 2006 Jun 8. Bioorg Med Chem. 2006. PMID: 16759871
Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.
Padmanilayam M, Scorneaux B, Dong Y, Chollet J, Matile H, Charman SA, Creek DJ, Charman WN, Tomas JS, Scheurer C, Wittlin S, Brun R, Vennerstrom JL. Padmanilayam M, et al. Among authors: vennerstrom jl. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5542-5. doi: 10.1016/j.bmcl.2006.08.046. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16931006
Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides.
Tang Y, Dong Y, Wittlin S, Charman SA, Chollet J, Chiu FC, Charman WN, Matile H, Urwyler H, Dorn A, Bajpai S, Wang X, Padmanilayam M, Karle JM, Brun R, Vennerstrom JL. Tang Y, et al. Among authors: vennerstrom jl. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1260-5. doi: 10.1016/j.bmcl.2006.12.007. Epub 2006 Dec 15. Bioorg Med Chem Lett. 2007. PMID: 17189686
134 results