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Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.
Leshchiner ES, Rush JS, Durney MA, Cao Z, Dančík V, Chittick B, Wu H, Petrone A, Bittker JA, Phillips A, Perez JR, Shamji AF, Kaushik VK, Daly MJ, Graham DB, Schreiber SL, Xavier RJ. Leshchiner ES, et al. Among authors: phillips a. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11392-11397. doi: 10.1073/pnas.1705748114. Epub 2017 Oct 9. Proc Natl Acad Sci U S A. 2017. PMID: 29073062 Free PMC article.
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.
Johannessen L, Sundberg TB, O'Connell DJ, Kolde R, Berstler J, Billings KJ, Khor B, Seashore-Ludlow B, Fassl A, Russell CN, Latorre IJ, Jiang B, Graham DB, Perez JR, Sicinski P, Phillips AJ, Schreiber SL, Gray NS, Shamji AF, Xavier RJ. Johannessen L, et al. Among authors: phillips aj. Nat Chem Biol. 2017 Oct;13(10):1102-1108. doi: 10.1038/nchembio.2458. Epub 2017 Aug 14. Nat Chem Biol. 2017. PMID: 28805801 Free PMC article.
Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo.
Sundberg TB, Liang Y, Wu H, Choi HG, Kim ND, Sim T, Johannessen L, Petrone A, Khor B, Graham DB, Latorre IJ, Phillips AJ, Schreiber SL, Perez J, Shamji AF, Gray NS, Xavier RJ. Sundberg TB, et al. Among authors: phillips aj. ACS Chem Biol. 2016 Aug 19;11(8):2105-11. doi: 10.1021/acschembio.6b00217. Epub 2016 Jun 6. ACS Chem Biol. 2016. PMID: 27224444 Free PMC article.
Efficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments.
Haftchenary S, Nelson SD Jr, Furst L, Dandapani S, Ferrara SJ, Bošković ŽV, Figueroa Lazú S, Guerrero AM, Serrano JC, Crews DK, Brackeen C, Mowat J, Brumby T, Bauser M, Schreiber SL, Phillips AJ. Haftchenary S, et al. ACS Comb Sci. 2016 Sep 12;18(9):569-74. doi: 10.1021/acscombsci.6b00050. Epub 2016 Aug 12. ACS Comb Sci. 2016. PMID: 27518324 Free PMC article.
Assessing the effect of health system resources on HIV and tuberculosis programmes in Malawi: a modelling study.
Mangal TD, Mohan S, Colbourn T, Collins JH, Graham M, Jahn A, Janoušková E, Lin IL, Smith RM, Mnjowe E, Molaro M, Mwenyenkulu TE, Nkhoma D, She B, Tamuri A, Revill P, Phillips AN, Mfutso-Bengo J, Hallett TB. Mangal TD, et al. Among authors: phillips an. Lancet Glob Health. 2024 Oct;12(10):e1638-e1648. doi: 10.1016/S2214-109X(24)00259-6. Lancet Glob Health. 2024. PMID: 39304236
From conceptualising to modelling structural determinants and interventions in HIV transmission dynamics models: a scoping review and methodological framework for evidence-based analyses.
Stannah J, Flores Anato JL, Pickles M, Larmarange J, Mitchell KM, Artenie A, Dumchev K, Niangoran S, Platt L, Terris-Prestholt F, Singh A, Stone J, Vickerman P, Phillips A, Johnson L, Maheu-Giroux M, Boily MC. Stannah J, et al. Among authors: phillips a. BMC Med. 2024 Sep 19;22(1):404. doi: 10.1186/s12916-024-03580-z. BMC Med. 2024. PMID: 39300441 Free PMC article. Review.
Individualized Pain Treatment in Chronic Pancreatitis (INPAIN): An International, Multicenter, Investigator-initiated, Prospective, Cohort Study.
Hagn-Meincke R, Dugic A, Agarwal A, Phillips AE, Waage A, Yadav D, Pillai D, Vivian E, de-Madaria E, Niazi IK, Easler J, Frøkjær JB, McNabb-Baltar J, Asferg LK, Faghih M, Montiel MBG, Cook M, Unnisa M, Tarnasky P, Hegyi P, Garg P, Nedergaard RB, Edwards R, Talukdar R, Farheen S, Olesen SS, Jagannath S, Schmidt S, Singh V, Hajnády Z, Drewes AM; International Pancreatic Pain Consortium. Hagn-Meincke R, et al. Among authors: phillips ae. Pancreas. 2024 Sep 12. doi: 10.1097/MPA.0000000000002388. Online ahead of print. Pancreas. 2024. PMID: 39259852
4,700 results