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A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D. Wang J, et al. Among authors: varani l. Cell. 2017 Sep 21;171(1):229-241.e15. doi: 10.1016/j.cell.2017.09.002. Cell. 2017. PMID: 28938115 Free PMC article.
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity.
Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, Quyen NT, Sukupolvi-Petty S, Navarro-Sanchez E, Young PR, de Silva AM, Rey FA, Varani L, Whitehead SS, Diamond MS, Harris E, Lanzavecchia A, Sallusto F. Beltramello M, et al. Among authors: varani l. Cell Host Microbe. 2010 Sep 16;8(3):271-83. doi: 10.1016/j.chom.2010.08.007. Cell Host Microbe. 2010. PMID: 20833378 Free PMC article.
Epitope mapping by solution NMR spectroscopy.
Bardelli M, Livoti E, Simonelli L, Pedotti M, Moraes A, Valente AP, Varani L. Bardelli M, et al. Among authors: varani l. J Mol Recognit. 2015 Jun;28(6):393-400. doi: 10.1002/jmr.2454. Epub 2015 Feb 27. J Mol Recognit. 2015. PMID: 25726811
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus.
Corti D, Zhao J, Pedotti M, Simonelli L, Agnihothram S, Fett C, Fernandez-Rodriguez B, Foglierini M, Agatic G, Vanzetta F, Gopal R, Langrish CJ, Barrett NA, Sallusto F, Baric RS, Varani L, Zambon M, Perlman S, Lanzavecchia A. Corti D, et al. Among authors: varani l. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10473-8. doi: 10.1073/pnas.1510199112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216974 Free PMC article.
87 results