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Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.
Khatamzas E, Hipp MM, Gaughan D, Pichulik T, Leslie A, Fernandes RA, Muraro D, Booth S, Zausmer K, Sun MY, Kessler B, Rowland-Jones S, Cerundolo V, Simmons A. Khatamzas E, et al. EMBO J. 2017 Oct 16;36(20):2998-3011. doi: 10.15252/embj.201695364. Epub 2017 Sep 18. EMBO J. 2017. PMID: 28923824 Free PMC article.
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.
Brain O, Owens BM, Pichulik T, Allan P, Khatamzas E, Leslie A, Steevels T, Sharma S, Mayer A, Catuneanu AM, Morton V, Sun MY, Jewell D, Coccia M, Harrison O, Maloy K, Schönefeldt S, Bornschein S, Liston A, Simmons A. Brain O, et al. Among authors: khatamzas e. Immunity. 2013 Sep 19;39(3):521-36. doi: 10.1016/j.immuni.2013.08.035. Immunity. 2013. PMID: 24054330 Free article.
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
Colak E, Leslie A, Zausmer K, Khatamzas E, Kubarenko AV, Pichulik T, Klimosch SN, Mayer A, Siggs O, Hector A, Fischer R, Klesser B, Rautanen A, Frank M, Hill AV, Manoury B, Beutler B, Hartl D, Simmons A, Weber AN. Colak E, et al. Among authors: khatamzas e. J Immunol. 2014 Jun 15;192(12):5963-73. doi: 10.4049/jimmunol.1303058. Epub 2014 May 9. J Immunol. 2014. PMID: 24813206 Free PMC article.
Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus.
Pichulik T, Khatamzas E, Liu X, Brain O, Delmiro Garcia M, Leslie A, Danis B, Mayer A, Baban D, Ragoussis J, Weber AN, Simmons A. Pichulik T, et al. Among authors: khatamzas e. Eur J Immunol. 2016 Jan;46(1):167-77. doi: 10.1002/eji.201444970. Epub 2015 Oct 30. Eur J Immunol. 2016. PMID: 26460926 Free PMC article.
42 results