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PYY plays a key role in the resolution of diabetes following bariatric surgery in humans.
Guida C, Stephen SD, Watson M, Dempster N, Larraufie P, Marjot T, Cargill T, Rickers L, Pavlides M, Tomlinson J, Cobbold JFL, Zhao CM, Chen D, Gribble F, Reimann F, Gillies R, Sgromo B, Rorsman P, Ryan JD, Ramracheya RD. Guida C, et al. EBioMedicine. 2019 Feb;40:67-76. doi: 10.1016/j.ebiom.2018.12.040. Epub 2019 Jan 11. EBioMedicine. 2019. PMID: 30639417 Free PMC article.
Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.
Vergari E, Denwood G, Salehi A, Zhang Q, Adam J, Alrifaiy A, Wernstedt Asterholm I, Benrick A, Chibalina MV, Eliasson L, Guida C, Hill TG, Hamilton A, Ramracheya R, Reimann F, Rorsman NJG, Spilliotis I, Tarasov AI, Walker JN, Rorsman P, Briant LJB. Vergari E, et al. Among authors: guida c. Nat Metab. 2020 Jan;2(1):32-40. doi: 10.1038/s42255-019-0158-0. Epub 2020 Jan 20. Nat Metab. 2020. PMID: 31993555 Free PMC article.
PYY, a Therapeutic Option for Type 2 Diabetes?
Guida C, Ramracheya R. Guida C, et al. Clin Med Insights Endocrinol Diabetes. 2020 Jan 22;13:1179551419892985. doi: 10.1177/1179551419892985. eCollection 2020. Clin Med Insights Endocrinol Diabetes. 2020. PMID: 32030069 Free PMC article. Review.
GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.
Gandasi NR, Gao R, Kothegala L, Pearce A, Santos C, Acreman S, Basco D, Benrick A, Chibalina MV, Clark A, Guida C, Harris M, Johnson PRV, Knudsen JG, Ma J, Miranda C, Shigeto M, Tarasov AI, Yeung HY, Thorens B, Asterholm IW, Zhang Q, Ramracheya R, Ladds G, Rorsman P. Gandasi NR, et al. Among authors: guida c. Diabetologia. 2024 Mar;67(3):528-546. doi: 10.1007/s00125-023-06060-w. Epub 2023 Dec 21. Diabetologia. 2024. PMID: 38127123 Free PMC article.
Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes.
Hill TG, Gao R, Benrick A, Kothegala L, Rorsman N, Santos C, Acreman S, Briant LJ, Dou H, Gandasi NR, Guida C, Haythorne E, Wallace M, Knudsen JG, Miranda C, Tolö J, Clark A, Davison L, Størling J, Tarasov A, Ashcroft FM, Rorsman P, Zhang Q. Hill TG, et al. Among authors: guida c. Nat Metab. 2024 Sep 23. doi: 10.1038/s42255-024-01139-z. Online ahead of print. Nat Metab. 2024. PMID: 39313541
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes.
Oduori OS, Murao N, Shimomura K, Takahashi H, Zhang Q, Dou H, Sakai S, Minami K, Chanclon B, Guida C, Kothegala L, Tolö J, Maejima Y, Yokoi N, Minami Y, Miki T, Rorsman P, Seino S. Oduori OS, et al. Among authors: guida c. J Clin Invest. 2020 Dec 1;130(12):6639-6655. doi: 10.1172/JCI140046. J Clin Invest. 2020. PMID: 33196462 Free PMC article.
153 results