Holton JM - Search Results

1

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.

Knott GJ, East-Seletsky A, Cofsky JC, Holton JM, Charles E, O'Connell MR, Doudna JA. Knott GJ, et al. Among authors: holton jm. Nat Struct Mol Biol. 2017 Oct;24(10):825-833. doi: 10.1038/nsmb.3466. Epub 2017 Sep 11. Nat Struct Mol Biol. 2017. PMID: 28892041 Free PMC article.

2

Covariance analysis of RNA recognition motifs identifies functionally linked amino acids.

Crowder S, Holton J, Alber T. Crowder S, et al. J Mol Biol. 2001 Jul 20;310(4):793-800. doi: 10.1006/jmbi.2001.4740. J Mol Biol. 2001. PMID: 11453688

3

Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.

Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH. Borovinskaya MA, et al. Among authors: holton jm. Nat Struct Mol Biol. 2007 Aug;14(8):727-32. doi: 10.1038/nsmb1271. Epub 2007 Jul 29. Nat Struct Mol Biol. 2007. PMID: 17660832

4

Structures of the intermediates of Kok's photosynthetic water oxidation clock.

Kern J, Chatterjee R, Young ID, Fuller FD, Lassalle L, Ibrahim M, Gul S, Fransson T, Brewster AS, Alonso-Mori R, Hussein R, Zhang M, Douthit L, de Lichtenberg C, Cheah MH, Shevela D, Wersig J, Seuffert I, Sokaras D, Pastor E, Weninger C, Kroll T, Sierra RG, Aller P, Butryn A, Orville AM, Liang M, Batyuk A, Koglin JE, Carbajo S, Boutet S, Moriarty NW, Holton JM, Dobbek H, Adams PD, Bergmann U, Sauter NK, Zouni A, Messinger J, Yano J, Yachandra VK. Kern J, et al. Among authors: holton jm. Nature. 2018 Nov;563(7731):421-425. doi: 10.1038/s41586-018-0681-2. Epub 2018 Nov 7. Nature. 2018. PMID: 30405241 Free PMC article.

5

Challenge data set for macromolecular multi-microcrystallography.

Holton JM. Holton JM. Acta Crystallogr D Struct Biol. 2019 Feb 1;75(Pt 2):113-122. doi: 10.1107/S2059798319001426. Epub 2019 Feb 6. Acta Crystallogr D Struct Biol. 2019. PMID: 30821701 Free PMC article.

6

Automated protein crystal structure determination using ELVES.

Holton J, Alber T. Holton J, et al. Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1537-42. doi: 10.1073/pnas.0306241101. Epub 2004 Jan 29. Proc Natl Acad Sci U S A. 2004. PMID: 14752198 Free PMC article.

7

Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.

Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA. Huang DT, et al. Among authors: holton jm. Nature. 2007 Jan 25;445(7126):394-8. doi: 10.1038/nature05490. Epub 2007 Jan 14. Nature. 2007. PMID: 17220875 Free PMC article.

8

Automated electron-density sampling reveals widespread conformational polymorphism in proteins.

Lang PT, Ng HL, Fraser JS, Corn JE, Echols N, Sales M, Holton JM, Alber T. Lang PT, et al. Among authors: holton jm. Protein Sci. 2010 Jul;19(7):1420-31. doi: 10.1002/pro.423. Protein Sci. 2010. PMID: 20499387 Free PMC article.

9

Accessing protein conformational ensembles using room-temperature X-ray crystallography.

Fraser JS, van den Bedem H, Samelson AJ, Lang PT, Holton JM, Echols N, Alber T. Fraser JS, et al. Among authors: holton jm. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16247-52. doi: 10.1073/pnas.1111325108. Epub 2011 Sep 14. Proc Natl Acad Sci U S A. 2011. PMID: 21918110 Free PMC article.

10

The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures.

Holton JM, Classen S, Frankel KA, Tainer JA. Holton JM, et al. FEBS J. 2014 Sep;281(18):4046-60. doi: 10.1111/febs.12922. Epub 2014 Sep 17. FEBS J. 2014. PMID: 25040949 Free PMC article.

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