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Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway.
Wang SC, Lin XL, Wang HY, Qin YJ, Chen L, Li J, Jia JS, Shen HF, Yang S, Xie RY, Wei F, Gao F, Rong XX, Yang J, Zhao WT, Zhang TT, Shi JW, Yao KT, Luo WR, Sun Y, Xiao D. Wang SC, et al. Among authors: chen l. Oncotarget. 2015 Nov 3;6(34):36713-30. doi: 10.18632/oncotarget.5457. Oncotarget. 2015. PMID: 26452025 Free PMC article.
NEK4 kinase regulates EMT to promote lung cancer metastasis.
Ding NH, Zhang L, Xiao Z, Rong ZX, Li Z, He J, Chen L, Ou DM, Liao WH, Sun LQ. Ding NH, et al. Among authors: chen l. J Cell Mol Med. 2018 Dec;22(12):5877-5887. doi: 10.1111/jcmm.13857. Epub 2018 Sep 24. J Cell Mol Med. 2018. PMID: 30247800 Free PMC article.
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