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A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies.
Gilormini PA, Thota VN, Fers-Lidou A, Ashmus RA, Nodwell M, Brockerman J, Kuo CW, Wang Y, Gray TE, Nitin, McDonagh AW, Guu SY, Ertunc N, Yeo D, Zandberg WF, Khoo KH, Britton R, Vocadlo DJ. Gilormini PA, et al. Among authors: khoo kh. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2314026121. doi: 10.1073/pnas.2314026121. Epub 2024 Jun 25. Proc Natl Acad Sci U S A. 2024. PMID: 38917011
Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Tsai YX, Chang NE, Reuter K, Chang HT, Yang TJ, von Bülow S, Sehrawat V, Zerrouki N, Tuffery M, Gecht M, Grothaus IL, Colombi Ciacchi L, Wang YS, Hsu MF, Khoo KH, Hummer G, Hsu SD, Hanus C, Sikora M. Tsai YX, et al. Among authors: khoo kh. Cell. 2024 Feb 29;187(5):1296-1311.e26. doi: 10.1016/j.cell.2024.01.034. Cell. 2024. PMID: 38428397 Free article.
293 results