Kadri H - Search Results

1

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain.

Salim M, Knowles TJ, Baker AT, Davey MS, Jeeves M, Sridhar P, Wilkie J, Willcox CR, Kadri H, Taher TE, Vantourout P, Hayday A, Mehellou Y, Mohammed F, Willcox BE. Salim M, et al. Among authors: kadri h. ACS Chem Biol. 2017 Oct 20;12(10):2631-2643. doi: 10.1021/acschembio.7b00694. Epub 2017 Sep 14. ACS Chem Biol. 2017. PMID: 28862425 Free PMC article.

2

Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of Vγ9/Vδ2 T-Cell Immune Responses.

Kadri H, Taher TE, Xu Q, Sharif M, Ashby E, Bryan RT, Willcox BE, Mehellou Y. Kadri H, et al. J Med Chem. 2020 Oct 8;63(19):11258-11270. doi: 10.1021/acs.jmedchem.0c01232. Epub 2020 Sep 29. J Med Chem. 2020. PMID: 32930595 Free PMC article.

3

The Photosensitising Clinical Agent Verteporfin Is an Inhibitor of SPAK and OSR1 Kinases.

AlAmri MA, Kadri H, Alderwick LJ, Jeeves M, Mehellou Y. AlAmri MA, et al. Among authors: kadri h. Chembiochem. 2018 Oct 4;19(19):2072-2080. doi: 10.1002/cbic.201800272. Epub 2018 Aug 22. Chembiochem. 2018. PMID: 29999233

4

C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25.

Mehellou Y, Alamri MA, Dhiani BA, Kadri H. Mehellou Y, et al. Among authors: kadri h. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1868-1873. doi: 10.1016/j.bbrc.2018.07.128. Epub 2018 Jul 27. Biochem Biophys Res Commun. 2018. PMID: 30060950

5

Towards the Development of Small-Molecule MO25 Binders as Potential Indirect SPAK/OSR1 Kinase Inhibitors.

Kadri H, Alamri MA, Navratilova IH, Alderwick LJ, Simpkins NS, Mehellou Y. Kadri H, et al. Chembiochem. 2017 Mar 2;18(5):460-465. doi: 10.1002/cbic.201600620. Epub 2017 Jan 30. Chembiochem. 2017. PMID: 28004876 Free article.

6

Nucleoside Phosphate and Phosphonate Prodrug Clinical Candidates.

Thornton PJ, Kadri H, Miccoli A, Mehellou Y. Thornton PJ, et al. Among authors: kadri h. J Med Chem. 2016 Dec 8;59(23):10400-10410. doi: 10.1021/acs.jmedchem.6b00523. Epub 2016 Sep 8. J Med Chem. 2016. PMID: 27559756 Review.

7

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.

Barini E, Miccoli A, Tinarelli F, Mulholland K, Kadri H, Khanim F, Stojanovski L, Read KD, Burness K, Blow JJ, Mehellou Y, Muqit MMK. Barini E, et al. Among authors: kadri h. Chembiochem. 2018 Mar 2;19(5):425-429. doi: 10.1002/cbic.201700500. Epub 2018 Jan 24. Chembiochem. 2018. PMID: 29226533 Free PMC article.

8

Niclosamide, a Drug with Many (Re)purposes.

Kadri H, Lambourne OA, Mehellou Y. Kadri H, et al. ChemMedChem. 2018 Jun 6;13(11):1088-1091. doi: 10.1002/cmdc.201800100. Epub 2018 May 8. ChemMedChem. 2018. PMID: 29603892 Free PMC article.

9

Rafoxanide and Closantel Inhibit SPAK and OSR1 Kinases by Binding to a Highly Conserved Allosteric Site on Their C-terminal Domains.

AlAmri MA, Kadri H, Alderwick LJ, Simpkins NS, Mehellou Y. AlAmri MA, et al. Among authors: kadri h. ChemMedChem. 2017 May 9;12(9):639-645. doi: 10.1002/cmdc.201700077. Epub 2017 Apr 12. ChemMedChem. 2017. PMID: 28371477 Free article.

10

Aryloxy Triester Phosphoramidates as Phosphoserine Prodrugs: A Proof of Concept Study.

Miccoli A, Dhiani BA, Thornton PJ, Lambourne OA, James E, Kadri H, Mehellou Y. Miccoli A, et al. Among authors: kadri h. ChemMedChem. 2020 Apr 20;15(8):671-674. doi: 10.1002/cmdc.202000034. Epub 2020 Mar 26. ChemMedChem. 2020. PMID: 32162793

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