Hewett DR - Search Results

1

HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1.

Vandyke K, Zeissig MN, Hewett DR, Martin SK, Mrozik KM, Cheong CM, Diamond P, To LB, Gronthos S, Peet DJ, Croucher PI, Zannettino ACW. Vandyke K, et al. Among authors: hewett dr. Cancer Res. 2017 Oct 15;77(20):5452-5463. doi: 10.1158/0008-5472.CAN-17-0115. Epub 2017 Aug 30. Cancer Res. 2017. PMID: 28855206

2

Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications.

Hiwase DK, Saunders V, Hewett D, Frede A, Zrim S, Dang P, Eadie L, To LB, Melo J, Kumar S, Hughes TP, White DL. Hiwase DK, et al. Clin Cancer Res. 2008 Jun 15;14(12):3881-8. doi: 10.1158/1078-0432.CCR-07-5095. Clin Cancer Res. 2008. PMID: 18559609 Free article.

3

SAMSN1 is a tumor suppressor gene in multiple myeloma.

Noll JE, Hewett DR, Williams SA, Vandyke K, Kok C, To LB, Zannettino AC. Noll JE, et al. Among authors: hewett dr. Neoplasia. 2014 Jul;16(7):572-85. doi: 10.1016/j.neo.2014.07.002. Neoplasia. 2014. PMID: 25117979 Free PMC article.

4

Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo.

Cheong CM, Chow AW, Fitter S, Hewett DR, Martin SK, Williams SA, To LB, Zannettino AC, Vandyke K. Cheong CM, et al. Among authors: hewett dr. Exp Cell Res. 2015 Mar 1;332(1):24-38. doi: 10.1016/j.yexcr.2015.01.006. Epub 2015 Jan 28. Exp Cell Res. 2015. PMID: 25637218

5

Therapeutic targeting of N-cadherin is an effective treatment for multiple myeloma.

Mrozik KM, Cheong CM, Hewett D, Chow AW, Blaschuk OW, Zannettino AC, Vandyke K. Mrozik KM, et al. Br J Haematol. 2015 Nov;171(3):387-99. doi: 10.1111/bjh.13596. Epub 2015 Jul 20. Br J Haematol. 2015. PMID: 26194766 Free article.

6

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.

Noll JE, Vandyke K, Hewett DR, Mrozik KM, Bala RJ, Williams SA, Kok CH, Zannettino AC. Noll JE, et al. Among authors: hewett dr. J Hematol Oncol. 2015 Oct 6;8:106. doi: 10.1186/s13045-015-0209-2. J Hematol Oncol. 2015. PMID: 26445238 Free PMC article.

7

Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma.

Dutta AK, Hewett DR, Fink JL, Grady JP, Zannettino ACW. Dutta AK, et al. Among authors: hewett dr. Br J Haematol. 2017 Jul;178(2):196-208. doi: 10.1111/bjh.14649. Epub 2017 May 3. Br J Haematol. 2017. PMID: 28466550 Free article. Review.

8

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.

Wallington-Beddoe CT, Bennett MK, Vandyke K, Davies L, Zebol JR, Moretti PAB, Pitman MR, Hewett DR, Zannettino ACW, Pitson SM. Wallington-Beddoe CT, et al. Among authors: hewett dr. Oncotarget. 2017 Jul 4;8(27):43602-43616. doi: 10.18632/oncotarget.17115. Oncotarget. 2017. PMID: 28467788 Free PMC article.

9

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment.

Hewett DR, Vandyke K, Lawrence DM, Friend N, Noll JE, Geoghegan JM, Croucher PI, Zannettino ACW. Hewett DR, et al. Neoplasia. 2017 Dec;19(12):972-981. doi: 10.1016/j.neo.2017.09.004. Epub 2017 Nov 5. Neoplasia. 2017. PMID: 29091798 Free PMC article.

10

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability.

Dutta AK, Fink JL, Grady JP, Morgan GJ, Mullighan CG, To LB, Hewett DR, Zannettino ACW. Dutta AK, et al. Among authors: hewett dr. Leukemia. 2019 Feb;33(2):457-468. doi: 10.1038/s41375-018-0206-x. Epub 2018 Jul 25. Leukemia. 2019. PMID: 30046162 Free PMC article.

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