Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

6,451 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.
Sugeno N, Hasegawa T, Tanaka N, Fukuda M, Wakabayashi K, Oshima R, Konno M, Miura E, Kikuchi A, Baba T, Anan T, Nakao M, Geisler S, Aoki M, Takeda A. Sugeno N, et al. Among authors: hasegawa t. J Biol Chem. 2014 Jun 27;289(26):18137-51. doi: 10.1074/jbc.M113.529461. Epub 2014 May 15. J Biol Chem. 2014. PMID: 24831002 Free PMC article.
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N. Oshima R, et al. Among authors: hasegawa t. Sci Rep. 2016 Apr 26;6:24997. doi: 10.1038/srep24997. Sci Rep. 2016. PMID: 27112194 Free PMC article.
Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking.
Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y, Aoki M. Yoshida S, et al. Among authors: hasegawa t. Hum Mol Genet. 2018 Mar 1;27(5):823-836. doi: 10.1093/hmg/ddy003. Hum Mol Genet. 2018. PMID: 29309590
[Cellular pathophysiology of Parkinson's disease].
Takeda A, Sugeno N, Hasegawa T, Kobayashi M, Kikuchi A. Takeda A, et al. Among authors: hasegawa t. Rinsho Shinkeigaku. 2008 Nov;48(11):984-5. doi: 10.5692/clinicalneurol.48.984. Rinsho Shinkeigaku. 2008. PMID: 19198139 Japanese.
Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis.
Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, Baba T, Takeda A, Kanzaki M, Wakabayashi K, Okano H, Aoki M. Kobayashi J, et al. Among authors: hasegawa t. FASEB J. 2019 Sep;33(9):10240-10256. doi: 10.1096/fj.201802051R. Epub 2019 Jun 18. FASEB J. 2019. PMID: 31211923
Altogether, these findings revealed a novel role of extracellular alpha-SYN on cellular trafficking of DAT and may provide a rationale for the cell type-specific, functional, and pathologic alterations in PD.-Kobayashi, J., Hasegawa, T., Sugeno, N., Yoshida, S., Aki …
Altogether, these findings revealed a novel role of extracellular alpha-SYN on cellular trafficking of DAT and may provide a rationale for t …
6,451 results