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Safety, pharmacokinetics and dose-response characteristics of GSK2269557, an inhaled PI3Kδ inhibitor under development for the treatment of COPD.
Cahn A, Hamblin JN, Begg M, Wilson R, Dunsire L, Sriskantharajah S, Montembault M, Leemereise CN, Galinanes-Garcia L, Watz H, Kirsten AM, Fuhr R, Hessel EM. Cahn A, et al. Among authors: galinanes garcia l. Pulm Pharmacol Ther. 2017 Oct;46:69-77. doi: 10.1016/j.pupt.2017.08.008. Epub 2017 Aug 17. Pulm Pharmacol Ther. 2017. PMID: 28823947 Free article. Clinical Trial.
The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans.
Thorneloe KS, Sepp A, Zhang S, Galinanes-Garcia L, Galette P, Al-Azzam W, Vugts DJ, van Dongen G, Elsinga P, Wiegers J, Glaudemans AWJM, Vincent V, Renaux J, Szapacs M, Birchler M, Cleveland M, Bergstrom M, Davies M. Thorneloe KS, et al. Among authors: galinanes garcia l. EJNMMI Res. 2019 May 21;9(1):45. doi: 10.1186/s13550-019-0514-9. EJNMMI Res. 2019. PMID: 31115711 Free PMC article.
Peptide-based, irreversible inhibitors of gamma-secretase activity.
Piper SC, Amtul Z, Galiñanes-Garcia L, Howard VG, Ziani-Cherif C, McLendon C, Rochette MJ, Fauq A, Golde TE, Murphy MP. Piper SC, et al. Among authors: galinanes garcia l. Biochem Biophys Res Commun. 2003 Jun 6;305(3):529-33. doi: 10.1016/s0006-291x(03)00828-3. Biochem Biophys Res Commun. 2003. PMID: 12763025