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N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis.
Edupuganti RR, Geiger S, Lindeboom RGH, Shi H, Hsu PJ, Lu Z, Wang SY, Baltissen MPA, Jansen PWTC, Rossa M, Müller M, Stunnenberg HG, He C, Carell T, Vermeulen M. Edupuganti RR, et al. Among authors: lu z. Nat Struct Mol Biol. 2017 Oct;24(10):870-878. doi: 10.1038/nsmb.3462. Epub 2017 Sep 4. Nat Struct Mol Biol. 2017. PMID: 28869609 Free PMC article.
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.
Ma H, Wang X, Cai J, Dai Q, Natchiar SK, Lv R, Chen K, Lu Z, Chen H, Shi YG, Lan F, Fan J, Klaholz BP, Pan T, Shi Y, He C. Ma H, et al. Among authors: lu z. Nat Chem Biol. 2019 Jan;15(1):88-94. doi: 10.1038/s41589-018-0184-3. Epub 2018 Dec 10. Nat Chem Biol. 2019. PMID: 30531910 Free PMC article.
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C. Zheng G, et al. Among authors: lu z. Mol Cell. 2013 Jan 10;49(1):18-29. doi: 10.1016/j.molcel.2012.10.015. Epub 2012 Nov 21. Mol Cell. 2013. PMID: 23177736 Free PMC article.
N6-methyladenosine-dependent regulation of messenger RNA stability.
Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han D, Fu Y, Parisien M, Dai Q, Jia G, Ren B, Pan T, He C. Wang X, et al. Among authors: lu z. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27. Nature. 2014. PMID: 24284625 Free PMC article.
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