Schoonen PM - Search Results

1

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

Schoonen PM, Talens F, Stok C, Gogola E, Heijink AM, Bouwman P, Foijer F, Tarsounas M, Blatter S, Jonkers J, Rottenberg S, van Vugt MATM. Schoonen PM, et al. Nat Commun. 2017 Jul 17;8:15981. doi: 10.1038/ncomms15981. Nat Commun. 2017. PMID: 28714471 Free PMC article.

2

Never tear us a-PARP: Dealing with DNA lesions during mitosis.

Schoonen PM, van Vugt MATM. Schoonen PM, et al. Mol Cell Oncol. 2017 Oct 31;5(1):e1382670. doi: 10.1080/23723556.2017.1382670. eCollection 2018. Mol Cell Oncol. 2017. PMID: 29404385 Free PMC article.

3

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells.

Schoonen PM, Kok YP, Wierenga E, Bakker B, Foijer F, Spierings DCJ, van Vugt MATM. Schoonen PM, et al. Mol Oncol. 2019 Nov;13(11):2422-2440. doi: 10.1002/1878-0261.12573. Epub 2019 Oct 21. Mol Oncol. 2019. PMID: 31529615 Free PMC article.

4

Replication stress: Driver and therapeutic target in genomically instable cancers.

Schoonen PM, Guerrero Llobet S, van Vugt MATM. Schoonen PM, et al. Adv Protein Chem Struct Biol. 2019;115:157-201. doi: 10.1016/bs.apcsb.2018.10.006. Epub 2018 Dec 28. Adv Protein Chem Struct Biol. 2019. PMID: 30798931 Review.

5

ATR inhibition preferentially targets homologous recombination-deficient tumor cells.

Krajewska M, Fehrmann RS, Schoonen PM, Labib S, de Vries EG, Franke L, van Vugt MA. Krajewska M, et al. Among authors: schoonen pm. Oncogene. 2015 Jun;34(26):3474-81. doi: 10.1038/onc.2014.276. Epub 2014 Sep 1. Oncogene. 2015. PMID: 25174396

6

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability.

Hengeveld RC, de Boer HR, Schoonen PM, de Vries EG, Lens SM, van Vugt MA. Hengeveld RC, et al. Among authors: schoonen pm. Dev Cell. 2015 Aug 24;34(4):466-74. doi: 10.1016/j.devcel.2015.06.014. Epub 2015 Aug 6. Dev Cell. 2015. PMID: 26256213 Free article.

7

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors.

Kok YP, Guerrero Llobet S, Schoonen PM, Everts M, Bhattacharya A, Fehrmann RSN, van den Tempel N, van Vugt MATM. Kok YP, et al. Among authors: schoonen pm. Oncogenesis. 2020 Oct 7;9(10):88. doi: 10.1038/s41389-020-00270-2. Oncogenesis. 2020. PMID: 33028815 Free PMC article.

8

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death.

Long JS, Schoonen PM, Graczyk D, O'Prey J, Ryan KM. Long JS, et al. Among authors: schoonen pm. Oncogene. 2015 Oct 1;34(40):5152-62. doi: 10.1038/onc.2014.436. Epub 2015 Feb 9. Oncogene. 2015. PMID: 25659586 Free PMC article.

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