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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.
Myers RW, Guan HP, Ehrhart J, Petrov A, Prahalada S, Tozzo E, Yang X, Kurtz MM, Trujillo M, Gonzalez Trotter D, Feng D, Xu S, Eiermann G, Holahan MA, Rubins D, Conarello S, Niu X, Souza SC, Miller C, Liu J, Lu K, Feng W, Li Y, Painter RE, Milligan JA, He H, Liu F, Ogawa A, Wisniewski D, Rohm RJ, Wang L, Bunzel M, Qian Y, Zhu W, Wang H, Bennet B, LaFranco Scheuch L, Fernandez GE, Li C, Klimas M, Zhou G, van Heek M, Biftu T, Weber A, Kelley DE, Thornberry N, Erion MD, Kemp DM, Sebhat IK. Myers RW, et al. Among authors: wang h, wang l. Science. 2017 Aug 4;357(6350):507-511. doi: 10.1126/science.aah5582. Epub 2017 Jul 13. Science. 2017. PMID: 28705990
mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting.
Al-Wassiti HA, Fabb SA, Grimley SL, Kochappan R, Ho JK, Wong CY, Tan CW, Payne TJ, Takanashi A, Lee CL, Mugan RS, Sicilia H, Teo SLY, McAuley J, Ellenberg P, Cooney JP, Davidson KC, Bowen R, Pellegrini M, Rockman S, Godfrey DI, Nolan TM, Wang LF, Deliyannis G, Purcell DFJ, Pouton CW. Al-Wassiti HA, et al. Among authors: wang lf. Mol Ther Methods Clin Dev. 2024 Nov 15;32(4):101380. doi: 10.1016/j.omtm.2024.101380. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39687732 Free PMC article.
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