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Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells.
Singha PK, Mäklin K, Vihavainen T, Laitinen T, Nevalainen TJ, Patil MR, Tonduru AK, Poso A, Laitinen JT, Savinainen JR. Singha PK, et al. Eur J Pharm Sci. 2020 Apr 7;149:105321. doi: 10.1016/j.ejps.2020.105321. Online ahead of print. Eur J Pharm Sci. 2020. PMID: 32275951
High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.
Aaltonen N, Singha PK, Jakupović H, Wirth T, Samaranayake H, Pasonen-Seppänen S, Rilla K, Varjosalo M, Edgington-Mitchell LE, Kasperkiewicz P, Drag M, Kälvälä S, Moisio E, Savinainen JR, Laitinen JT. Aaltonen N, et al. Among authors: singha pk. Biol Proced Online. 2020 Mar 15;22:6. doi: 10.1186/s12575-020-00118-4. eCollection 2020. Biol Proced Online. 2020. PMID: 32190011 Free PMC article.
Effect of channel morphological changes on wetland transformation.
Pal S, Debanshi S, Singha P, Ghosh R, Ghosh S, Mukhopadhyay S, Bhattacharaya A, Let S, Das P, Let M. Pal S, et al. Among authors: singha p. Sci Total Environ. 2024 Sep 10;942:173802. doi: 10.1016/j.scitotenv.2024.173802. Epub 2024 Jun 5. Sci Total Environ. 2024. PMID: 38848908
124 results