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Isoalantolactone inhibits IKKβ kinase activity to interrupt the NF-κB/COX-2-mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma.
Xing JS, Wang X, Lan YL, Lou JC, Ma B, Zhu T, Zhang H, Wang D, Yu Z, Yuan Z, Li XY, Zhang B. Xing JS, et al. Among authors: zhang b, zhang h. Cancer Med. 2019 Apr;8(4):1655-1670. doi: 10.1002/cam4.2013. Epub 2019 Feb 10. Cancer Med. 2019. PMID: 30740911 Free PMC article.
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