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Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.
Zhao R, Yeung SC, Chen J, Iwakuma T, Su CH, Chen B, Qu C, Zhang F, Chen YT, Lin YL, Lee DF, Jin F, Zhu R, Shaikenov T, Sarbassov D, Sahin A, Wang H, Wang H, Lai CC, Tsai FJ, Lozano G, Lee MH. Zhao R, et al. J Clin Invest. 2011 Mar;121(3):851-65. doi: 10.1172/JCI44111. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317535 Free PMC article.
High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia.
Zeng Z, Liu W, Tsao T, Qiu Y, Zhao Y, Samudio I, Sarbassov DD, Kornblau SM, Baggerly KA, Kantarjian HM, Konopleva M, Andreeff M. Zeng Z, et al. Among authors: sarbassov dd. Haematologica. 2017 Sep;102(9):1537-1548. doi: 10.3324/haematol.2016.162230. Epub 2017 Jun 28. Haematologica. 2017. PMID: 28659338 Free PMC article.
Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas.
Gallardo M, Malaney P, Aitken MJL, Zhang X, Link TM, Shah V, Alybayev S, Wu MH, Pageon LR, Ma H, Jacamo R, Yu L, Xu-Monette ZY, Steinman H, Lee HJ, Sarbassov D, Rapado I, Barton MC, Martinez-Lopez J, Bueso-Ramos C, Young KH, Post SM. Gallardo M, et al. J Natl Cancer Inst. 2020 Jan 1;112(1):95-106. doi: 10.1093/jnci/djz078. J Natl Cancer Inst. 2020. PMID: 31077320 Free PMC article.
A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics.
Wu X, Park M, Sarbassova DA, Ying H, Lee MG, Bhattacharya R, Ellis L, Peterson CB, Hung MC, Lin HK, Bersimbaev RI, Song MS, Sarbassov DD. Wu X, et al. Among authors: sarbassov dd. Int J Cancer. 2020 May 15;146(10):2822-2828. doi: 10.1002/ijc.32658. Epub 2019 Oct 8. Int J Cancer. 2020. PMID: 31472018 Free PMC article.
Akt: a key transducer in cancer.
Tsai PJ, Lai YH, Manne RK, Tsai YS, Sarbassov D, Lin HK. Tsai PJ, et al. J Biomed Sci. 2022 Oct 1;29(1):76. doi: 10.1186/s12929-022-00860-9. J Biomed Sci. 2022. PMID: 36180910 Free PMC article. Review.
42 results