Orkin SH - Search Results

1

PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer.

Hsu JH, Hubbell-Engler B, Adelmant G, Huang J, Joyce CE, Vazquez F, Weir BA, Montgomery P, Tsherniak A, Giacomelli AO, Perry JA, Trowbridge J, Fujiwara Y, Cowley GS, Xie H, Kim W, Novina CD, Hahn WC, Marto JA, Orkin SH. Hsu JH, et al. Among authors: orkin sh. Cancer Res. 2017 Sep 1;77(17):4613-4625. doi: 10.1158/0008-5472.CAN-17-0216. Epub 2017 Jun 27. Cancer Res. 2017. PMID: 28655788 Free PMC article.

2

Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells.

Crossley M, Whitelaw E, Perkins A, Williams G, Fujiwara Y, Orkin SH. Crossley M, et al. Among authors: orkin sh. Mol Cell Biol. 1996 Apr;16(4):1695-705. doi: 10.1128/MCB.16.4.1695. Mol Cell Biol. 1996. PMID: 8657145 Free PMC article.

3

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages.

Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. Porcher C, et al. Among authors: orkin sh. Cell. 1996 Jul 12;86(1):47-57. doi: 10.1016/s0092-8674(00)80076-8. Cell. 1996. PMID: 8689686 Free article.

4

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

Fujiwara Y, Browne CP, Cunniff K, Goff SC, Orkin SH. Fujiwara Y, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12355-8. doi: 10.1073/pnas.93.22.12355. Proc Natl Acad Sci U S A. 1996. PMID: 8901585 Free PMC article.

5

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

McDevitt MA, Shivdasani RA, Fujiwara Y, Yang H, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6781-5. doi: 10.1073/pnas.94.13.6781. Proc Natl Acad Sci U S A. 1997. PMID: 9192642 Free PMC article.

6

An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.

McDevitt MA, Fujiwara Y, Shivdasani RA, Orkin SH. McDevitt MA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7976-81. doi: 10.1073/pnas.94.15.7976. Proc Natl Acad Sci U S A. 1997. PMID: 9223298 Free PMC article.

7

FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation.

Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, Weiss MJ, Crossley M, Orkin SH. Tsang AP, et al. Among authors: orkin sh. Cell. 1997 Jul 11;90(1):109-19. doi: 10.1016/s0092-8674(00)80318-9. Cell. 1997. PMID: 9230307 Free article.

8

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.

Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. Shivdasani RA, et al. Among authors: orkin sh. EMBO J. 1997 Jul 1;16(13):3965-73. doi: 10.1093/emboj/16.13.3965. EMBO J. 1997. PMID: 9233806 Free PMC article.

9

Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL.

Wang LC, Kuo F, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH. Wang LC, et al. Among authors: orkin sh. EMBO J. 1997 Jul 16;16(14):4374-83. doi: 10.1093/emboj/16.14.4374. EMBO J. 1997. PMID: 9250681 Free PMC article.

10

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation.

Visvader JE, Mao X, Fujiwara Y, Hahm K, Orkin SH. Visvader JE, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13707-12. doi: 10.1073/pnas.94.25.13707. Proc Natl Acad Sci U S A. 1997. PMID: 9391090 Free PMC article.

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