Hirbawi J - Search Results

1

The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.

Hirbawi J, Bialkowska K, Bledzka KM, Liu J, Fukuda K, Qin J, Plow EF. Hirbawi J, et al. J Biol Chem. 2017 Aug 25;292(34):14258-14269. doi: 10.1074/jbc.M117.776195. Epub 2017 Jun 26. J Biol Chem. 2017. PMID: 28652408 Free PMC article.

2

Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation.

Zhu L, Yang J, Bromberger T, Holly A, Lu F, Liu H, Sun K, Klapproth S, Hirbawi J, Byzova TV, Plow EF, Moser M, Qin J. Zhu L, et al. Among authors: hirbawi j. Nat Commun. 2017 Nov 23;8(1):1744. doi: 10.1038/s41467-017-01822-8. Nat Commun. 2017. PMID: 29170462 Free PMC article.

3

Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.

Liu J, Fukuda K, Xu Z, Ma YQ, Hirbawi J, Mao X, Wu C, Plow EF, Qin J. Liu J, et al. Among authors: hirbawi j. J Biol Chem. 2011 Dec 16;286(50):43334-42. doi: 10.1074/jbc.M111.295352. Epub 2011 Oct 26. J Biol Chem. 2011. PMID: 22030399 Free PMC article.

4

Membrane binding of the N-terminal ubiquitin-like domain of kindlin-2 is crucial for its regulation of integrin activation.

Perera HD, Ma YQ, Yang J, Hirbawi J, Plow EF, Qin J. Perera HD, et al. Among authors: hirbawi j. Structure. 2011 Nov 9;19(11):1664-71. doi: 10.1016/j.str.2011.08.012. Structure. 2011. PMID: 22078565 Free PMC article.

5

Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.

Yang J, Zhu L, Zhang H, Hirbawi J, Fukuda K, Dwivedi P, Liu J, Byzova T, Plow EF, Wu J, Qin J. Yang J, et al. Among authors: hirbawi j. Nat Commun. 2014 Dec 18;5:5880. doi: 10.1038/ncomms6880. Nat Commun. 2014. PMID: 25520155 Free PMC article.

6

A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.

Song X, Yang J, Hirbawi J, Ye S, Perera HD, Goksoy E, Dwivedi P, Plow EF, Zhang R, Qin J. Song X, et al. Among authors: hirbawi j. Cell Res. 2012 Nov;22(11):1533-45. doi: 10.1038/cr.2012.97. Epub 2012 Jun 19. Cell Res. 2012. PMID: 22710802 Free PMC article.

7

Amino acid region 1000-1008 of factor V is a dynamic regulator for the emergence of procoagulant activity.

Wiencek JR, Na M, Hirbawi J, Kalafatis M. Wiencek JR, et al. Among authors: hirbawi j. J Biol Chem. 2013 Dec 27;288(52):37026-38. doi: 10.1074/jbc.M113.462374. Epub 2013 Oct 31. J Biol Chem. 2013. PMID: 24178294 Free PMC article.

8

The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin.

Wiencek JR, Hirbawi J, Yee VC, Kalafatis M. Wiencek JR, et al. Among authors: hirbawi j. J Biol Chem. 2016 Jan 22;291(4):1565-1581. doi: 10.1074/jbc.M115.691956. Epub 2015 Nov 24. J Biol Chem. 2016. PMID: 26601957 Free PMC article.

9

Role of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase.

Hirbawi J, Bukys MA, Barhoover MA, Erdogan E, Kalafatis M. Hirbawi J, et al. Biochemistry. 2008 Jul 29;47(30):7963-74. doi: 10.1021/bi800593k. Epub 2008 Jul 1. Biochemistry. 2008. PMID: 18590276 Free PMC article.

10

Contribution of amino acid region 659-663 of Factor Va heavy chain to the activity of factor Xa within prothrombinase.

Hirbawi J, Vaughn JL, Bukys MA, Vos HL, Kalafatis M. Hirbawi J, et al. Biochemistry. 2010 Oct 5;49(39):8520-34. doi: 10.1021/bi101097t. Epub 2010 Sep 13. Biochemistry. 2010. PMID: 20722419 Free PMC article.

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