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Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Heggermont WA, Papageorgiou AP, Quaegebeur A, Deckx S, Carai P, Verhesen W, Eelen G, Schoors S, van Leeuwen R, Alekseev S, Elzenaar I, Vinckier S, Pokreisz P, Walravens AS, Gijsbers R, Van Den Haute C, Nickel A, Schroen B, van Bilsen M, Janssens S, Maack C, Pinto Y, Carmeliet P, Heymans S. Heggermont WA, et al. Among authors: van bilsen m, van leeuwen r, van den haute c. Circulation. 2017 Aug 22;136(8):747-761. doi: 10.1161/CIRCULATIONAHA.116.024171. Epub 2017 Jun 13. Circulation. 2017. PMID: 28611091
Peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta/delta, but not PPARgamma, modulate the expression of genes involved in cardiac lipid metabolism.
Gilde AJ, van der Lee KA, Willemsen PH, Chinetti G, van der Leij FR, van der Vusse GJ, Staels B, van Bilsen M. Gilde AJ, et al. Among authors: van der lee ka, van bilsen m, van der leij fr, van der vusse gj. Circ Res. 2003 Mar 21;92(5):518-24. doi: 10.1161/01.RES.0000060700.55247.7C. Epub 2003 Feb 6. Circ Res. 2003. PMID: 12600885
17beta-estradiol antagonizes cardiomyocyte hypertrophy by autocrine/paracrine stimulation of a guanylyl cyclase A receptor-cyclic guanosine monophosphate-dependent protein kinase pathway.
Babiker FA, De Windt LJ, van Eickels M, Thijssen V, Bronsaer RJ, Grohé C, van Bilsen M, Doevendans PA. Babiker FA, et al. Among authors: van eickels m, van bilsen m. Circulation. 2004 Jan 20;109(2):269-76. doi: 10.1161/01.CIR.0000105682.85732.BD. Epub 2004 Jan 12. Circulation. 2004. PMID: 14718400
Transcriptomic analysis of PPARalpha-dependent alterations during cardiac hypertrophy.
Smeets PJ, de Vogel-van den Bosch HM, Willemsen PH, Stassen AP, Ayoubi T, van der Vusse GJ, van Bilsen M. Smeets PJ, et al. Among authors: van bilsen m, van der vusse gj. Physiol Genomics. 2008 Dec 12;36(1):15-23. doi: 10.1152/physiolgenomics.90296.2008. Epub 2008 Sep 23. Physiol Genomics. 2008. PMID: 18812456
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.
Heymans S, Hirsch E, Anker SD, Aukrust P, Balligand JL, Cohen-Tervaert JW, Drexler H, Filippatos G, Felix SB, Gullestad L, Hilfiker-Kleiner D, Janssens S, Latini R, Neubauer G, Paulus WJ, Pieske B, Ponikowski P, Schroen B, Schultheiss HP, Tschöpe C, Van Bilsen M, Zannad F, McMurray J, Shah AM. Heymans S, et al. Among authors: van bilsen m. Eur J Heart Fail. 2009 Feb;11(2):119-29. doi: 10.1093/eurjhf/hfn043. Eur J Heart Fail. 2009. PMID: 19168509 Free PMC article. Review.
Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.
Georgiadi A, Lichtenstein L, Degenhardt T, Boekschoten MV, van Bilsen M, Desvergne B, Müller M, Kersten S. Georgiadi A, et al. Among authors: van bilsen m. Circ Res. 2010 Jun 11;106(11):1712-21. doi: 10.1161/CIRCRESAHA.110.217380. Epub 2010 Apr 8. Circ Res. 2010. PMID: 20378851
A diet rich in unsaturated fatty acids prevents progression toward heart failure in a rabbit model of pressure and volume overload.
Den Ruijter HM, Verkerk AO, Schumacher CA, Houten SM, Belterman CN, Baartscheer A, Brouwer IA, van Bilsen M, de Roos B, Coronel R. Den Ruijter HM, et al. Among authors: van bilsen m. Circ Heart Fail. 2012 May 1;5(3):376-84. doi: 10.1161/CIRCHEARTFAILURE.111.963116. Epub 2012 Apr 2. Circ Heart Fail. 2012. PMID: 22474247 Free article.
Macrophage microRNA-155 promotes cardiac hypertrophy and failure.
Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, de Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Heymans S, et al. Among authors: van leeuwen re, van bilsen m. Circulation. 2013 Sep 24;128(13):1420-32. doi: 10.1161/CIRCULATIONAHA.112.001357. Epub 2013 Aug 16. Circulation. 2013. PMID: 23956210
142 results