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Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial.
Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Cantrell JA, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. Among authors: poole st. J Infect Dis. 2017 Jul 1;216(1):7-13. doi: 10.1093/infdis/jix144. J Infect Dis. 2017. PMID: 28541500 Clinical Trial.
Oral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrhea.
Talaat KR, Porter CK, Bourgeois AL, Lee TK, Duplessis CA, Maciel M Jr, Gutierrez RL, DeNearing B, Adjoodani B, Adkinson R, Testa KJ, Feijoo B, Alcala AN, Brubaker J, Beselman A, Chakraborty S, Sack D, Halpern J, Trop S, Wu H, Jiao J, Sullivan E, Riddle MS, Joseph SS, Poole ST, Prouty MG. Talaat KR, et al. Among authors: poole st. Gut Microbes. 2020 Nov 9;12(1):1732852. doi: 10.1080/19490976.2020.1732852. Epub 2020 Mar 13. Gut Microbes. 2020. PMID: 32167011 Free PMC article. Clinical Trial.
Hyperimmune Bovine Colostral Anti-CS17 Antibodies Protect Against Enterotoxigenic Escherichia coli Diarrhea in a Randomized, Doubled-Blind, Placebo-Controlled Human Infection Model.
Savarino SJ, McKenzie R, Tribble DR, Porter CK, O'Dowd A, Sincock SA, Poole ST, DeNearing B, Woods CM, Kim H, Grahek SL, Brinkley C, Crabb JH, Bourgeois AL. Savarino SJ, et al. Among authors: poole st. J Infect Dis. 2019 Jul 2;220(3):505-513. doi: 10.1093/infdis/jiz135. J Infect Dis. 2019. PMID: 30897198 Clinical Trial.
Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin-Heat-Labile Toxin Chimera.
O'Dowd A, Maciel M Jr, Poole ST, Jobling MG, Rollenhagen JE, Woods CM, Sincock SA, McVeigh AL, Gregory MJ, Maves RC, Prouty MG, Holmes RK, Savarino SJ. O'Dowd A, et al. Among authors: poole st. Infect Immun. 2020 Oct 19;88(11):e00252-20. doi: 10.1128/IAI.00252-20. Print 2020 Oct 19. Infect Immun. 2020. PMID: 32839188 Free PMC article.
Intradermal or Sublingual Delivery and Heat-Labile Enterotoxin Proteins Shape Immunologic Responses to a CFA/I Fimbria-Derived Subunit Antigen Vaccine against Enterotoxigenic Escherichia coli.
Maciel M Jr, Bauer D, Baudier RL, Bitoun J, Clements JD, Poole ST, Smith MA, Kaminski RW, Savarino SJ, Norton EB. Maciel M Jr, et al. Among authors: poole st. Infect Immun. 2019 Oct 18;87(11):e00460-19. doi: 10.1128/IAI.00460-19. Print 2019 Nov. Infect Immun. 2019. PMID: 31427449 Free PMC article.
Evaluation of transcutaneous immunization as a delivery route for an enterotoxigenic E. coli adhesin-based vaccine with CfaE, the colonization factor antigen 1 (CFA/I) tip adhesin.
Rollenhagen JE, Woods CM, O'Dowd A, Poole ST, Tian JH, Guebre-Xabier M, Ellingsworth L, Prouty MG, Glenn G, Savarino SJ. Rollenhagen JE, et al. Among authors: poole st. Vaccine. 2019 Sep 30;37(42):6134-6138. doi: 10.1016/j.vaccine.2019.08.057. Epub 2019 Sep 3. Vaccine. 2019. PMID: 31492474 Free article.
89 results