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Page 1
Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.
Lassalas P, Oukoloff K, Makani V, James M, Tran V, Yao Y, Huang L, Vijayendran K, Monti L, Trojanowski JQ, Lee VM, Kozlowski MC, Smith AB 3rd, Brunden KR, Ballatore C. Lassalas P, et al. Among authors: oukoloff k. ACS Med Chem Lett. 2017 Jul 5;8(8):864-868. doi: 10.1021/acsmedchemlett.7b00212. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835803 Free PMC article.
1,2,4-Triazolo[1,5-a]pyrimidines in drug design.
Oukoloff K, Lucero B, Francisco KR, Brunden KR, Ballatore C. Oukoloff K, et al. Eur J Med Chem. 2019 Mar 1;165:332-346. doi: 10.1016/j.ejmech.2019.01.027. Epub 2019 Jan 14. Eur J Med Chem. 2019. PMID: 30703745 Free PMC article. Review.
Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro.
Monti L, Cornec AS, Oukoloff K, Kovalevich J, Prijs K, Alle T, Brunden KR, Smith AB 3rd, El-Sakkary N, Liu LJ, Syed A, Skinner DE, Ballatore C, Caffrey CR. Monti L, et al. Among authors: oukoloff k. ACS Infect Dis. 2021 May 14;7(5):1089-1103. doi: 10.1021/acsinfecdis.0c00508. Epub 2020 Oct 31. ACS Infect Dis. 2021. PMID: 33135408 Free PMC article.
Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies.
Oukoloff K, Nzou G, Varricchio C, Lucero B, Alle T, Kovalevich J, Monti L, Cornec AS, Yao Y, James MJ, Trojanowski JQ, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Oukoloff K, et al. J Med Chem. 2021 Jan 28;64(2):1073-1102. doi: 10.1021/acs.jmedchem.0c01605. Epub 2021 Jan 7. J Med Chem. 2021. PMID: 33411523 Free PMC article.
Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells.
Lopez-Ramirez MA, McCurdy S, Li W, Haynes MK, Hale P, Francisco K, Oukoloff K, Bautista M, Choi CHJ, Sun H, Gongol B, Shyy JY, Ballatore C, Sklar LA, Gingras AR. Lopez-Ramirez MA, et al. Among authors: oukoloff k. FASEB Bioadv. 2021 Feb 18;3(5):334-355. doi: 10.1096/fba.2020-00141. eCollection 2021 May. FASEB Bioadv. 2021. PMID: 33977234 Free PMC article.
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: oukoloff k. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
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