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W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
Li T, Lin GY, Zhong L, Zhou Y, Wang J, Zhu Y, Feng Y, Cai XQ, Liu Q, Nosjean O, Boutin JA, Renard P, Yang DH, Wang MW. Li T, et al. Among authors: renard p. Acta Pharmacol Sin. 2017 Jul;38(7):1024-1037. doi: 10.1038/aps.2017.15. Epub 2017 May 15. Acta Pharmacol Sin. 2017. PMID: 28502980 Free PMC article.
New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Audinot V, Mailliet F, Lahaye-Brasseur C, Bonnaud A, Le Gall A, Amossé C, Dromaint S, Rodriguez M, Nagel N, Galizzi JP, Malpaux B, Guillaumet G, Lesieur D, Lefoulon F, Renard P, Delagrange P, Boutin JA. Audinot V, et al. Among authors: renard p. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):553-61. doi: 10.1007/s00210-003-0751-2. Epub 2003 May 23. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12764576
Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.
Mésangeau C, Pérès B, Descamps-François C, Chavatte P, Audinot V, Coumailleau S, Boutin JA, Delagrange P, Bennejean C, Renard P, Caignard DH, Berthelot P, Yous S. Mésangeau C, et al. Among authors: renard p. Bioorg Med Chem. 2010 May 15;18(10):3426-36. doi: 10.1016/j.bmc.2010.04.008. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20444610
Therapeutic perspectives for melatonin agonists and antagonists.
Delagrange P, Atkinson J, Boutin JA, Casteilla L, Lesieur D, Misslin R, Pellissier S, Pénicaud L, Renard P. Delagrange P, et al. Among authors: renard p. J Neuroendocrinol. 2003 Apr;15(4):442-8. doi: 10.1046/j.1365-2826.2003.01016.x. J Neuroendocrinol. 2003. PMID: 12622848 Review.
487 results