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Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.
Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA. Orcholski ME, et al. Among authors: alastalo tp. Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L252-L266. doi: 10.1152/ajplung.00453.2016. Epub 2017 May 4. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28473326 Free PMC article.
Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension.
de Jesus Perez VA, Yuan K, Lyuksyutova MA, Dewey F, Orcholski ME, Shuffle EM, Mathur M, Yancy L Jr, Rojas V, Li CG, Cao A, Alastalo TP, Khazeni N, Cimprich KA, Butte AJ, Ashley E, Zamanian RT. de Jesus Perez VA, et al. Among authors: alastalo tp. Am J Respir Crit Care Med. 2014 May 15;189(10):1260-72. doi: 10.1164/rccm.201310-1749OC. Am J Respir Crit Care Med. 2014. PMID: 24702692 Free PMC article.
Targeting the Wnt signaling pathways in pulmonary arterial hypertension.
de Jesus Perez V, Yuan K, Alastalo TP, Spiekerkoetter E, Rabinovitch M. de Jesus Perez V, et al. Among authors: alastalo tp. Drug Discov Today. 2014 Aug;19(8):1270-6. doi: 10.1016/j.drudis.2014.06.014. Epub 2014 Jun 20. Drug Discov Today. 2014. PMID: 24955837 Free PMC article. Review.
Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension.
Helenius MH, Vattulainen S, Orcholski M, Aho J, Komulainen A, Taimen P, Wang L, de Jesus Perez VA, Koskenvuo JW, Alastalo TP. Helenius MH, et al. Among authors: alastalo tp. Am J Physiol Lung Cell Mol Physiol. 2015 May 15;308(10):L1046-57. doi: 10.1152/ajplung.00340.2014. Epub 2015 Mar 27. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25820525 Free article. Clinical Trial.
Loss of PPARγ in endothelial cells leads to impaired angiogenesis.
Vattulainen-Collanus S, Akinrinade O, Li M, Koskenvuo M, Li CG, Rao SP, de Jesus Perez V, Yuan K, Sawada H, Koskenvuo JW, Alvira C, Rabinovitch M, Alastalo TP. Vattulainen-Collanus S, et al. Among authors: alastalo tp. J Cell Sci. 2016 Feb 15;129(4):693-705. doi: 10.1242/jcs.169011. Epub 2016 Jan 7. J Cell Sci. 2016. PMID: 26743080 Free PMC article.
S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4.
Spiekerkoetter E, Guignabert C, de Jesus Perez V, Alastalo TP, Powers JM, Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. Spiekerkoetter E, et al. Among authors: alastalo tp. Circ Res. 2009 Sep 25;105(7):639-47, 13 p following 647. doi: 10.1161/CIRCRESAHA.109.205120. Epub 2009 Aug 27. Circ Res. 2009. PMID: 19713532 Free PMC article.
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.
Lee SJ, Smith A, Guo L, Alastalo TP, Li M, Sawada H, Liu X, Chen ZH, Ifedigbo E, Jin Y, Feghali-Bostwick C, Ryter SW, Kim HP, Rabinovitch M, Choi AM. Lee SJ, et al. Among authors: alastalo tp. Am J Respir Crit Care Med. 2011 Mar 1;183(5):649-58. doi: 10.1164/rccm.201005-0746OC. Epub 2010 Oct 1. Am J Respir Crit Care Med. 2011. PMID: 20889906 Free PMC article.
55 results