McLoughlin SM - Search Results

1

Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors.

Wilsbacher JL, Cheng M, Cheng D, Trammell SAJ, Shi Y, Guo J, Koeniger SL, Kovar PJ, He Y, Selvaraju S, Heyman HR, Sorensen BK, Clark RF, Hansen TM, Longenecker KL, Raich D, Korepanova AV, Cepa S, Towne DL, Abraham VC, Tang H, Richardson PL, McLoughlin SM, Badagnani I, Curtin ML, Michaelides MR, Maag D, Buchanan FG, Chiang GG, Gao W, Rosenberg SH, Brenner C, Tse C. Wilsbacher JL, et al. Among authors: mcloughlin sm. Mol Cancer Ther. 2017 Jul;16(7):1236-1245. doi: 10.1158/1535-7163.MCT-16-0819. Epub 2017 May 3. Mol Cancer Ther. 2017. PMID: 28468779

2

Target Identification of Compounds from a Cell Viability Phenotypic Screen Using a Bead/Lysate-Based Affinity Capture Platform.

Tang H, Duggan S, Richardson PL, Marin V, Warder SE, McLoughlin SM. Tang H, et al. Among authors: mcloughlin sm. J Biomol Screen. 2016 Feb;21(2):201-11. doi: 10.1177/1087057115622431. Epub 2015 Dec 16. J Biomol Screen. 2016. PMID: 26676096

3

Emerging Approaches for the Identification of Protein Targets of Small Molecules - A Practitioners' Perspective.

Comess KM, McLoughlin SM, Oyer JA, Richardson PL, Stöckmann H, Vasudevan A, Warder SE. Comess KM, et al. Among authors: mcloughlin sm. J Med Chem. 2018 Oct 11;61(19):8504-8535. doi: 10.1021/acs.jmedchem.7b01921. Epub 2018 Jun 6. J Med Chem. 2018. PMID: 29718665

4

Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition.

Warder SE, Tucker LA, McLoughlin SM, Strelitzer TJ, Meuth JL, Zhang Q, Sheppard GS, Richardson PL, Lesniewski R, Davidsen SK, Bell RL, Rogers JC, Wang J. Warder SE, et al. Among authors: mcloughlin sm. J Proteome Res. 2008 Nov;7(11):4807-20. doi: 10.1021/pr800388p. Epub 2008 Oct 2. J Proteome Res. 2008. PMID: 18828628

5

Transmembrane TNF-dependent uptake of anti-TNF antibodies.

Deora A, Hegde S, Lee J, Choi CH, Chang Q, Lee C, Eaton L, Tang H, Wang D, Lee D, Michalak M, Tomlinson M, Tao Q, Gaur N, Harvey B, McLoughlin S, Labkovsky B, Ghayur T. Deora A, et al. MAbs. 2017 May/Jun;9(4):680-695. doi: 10.1080/19420862.2017.1304869. Epub 2017 Mar 21. MAbs. 2017. PMID: 28323513 Free PMC article.

6

Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.

Shah OJ, Lin X, Li L, Huang X, Li J, Anderson MG, Tang H, Rodriguez LE, Warder SE, McLoughlin S, Chen J, Palma J, Glaser KB, Donawho CK, Fesik SW, Shen Y. Shah OJ, et al. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12634-9. doi: 10.1073/pnas.0913615107. Epub 2010 Jun 28. Proc Natl Acad Sci U S A. 2010. PMID: 20616035 Free PMC article.

7

Processing complex mixtures of intact proteins for direct analysis by mass spectrometry.

Meng F, Cargile BJ, Patrie SM, Johnson JR, McLoughlin SM, Kelleher NL. Meng F, et al. Among authors: mcloughlin sm. Anal Chem. 2002 Jul 1;74(13):2923-9. doi: 10.1021/ac020049i. Anal Chem. 2002. PMID: 12141648

8

Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase.

Yin J, Straight PD, McLoughlin SM, Zhou Z, Lin AJ, Golan DE, Kelleher NL, Kolter R, Walsh CT. Yin J, et al. Among authors: mcloughlin sm. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15815-20. doi: 10.1073/pnas.0507705102. Epub 2005 Oct 19. Proc Natl Acad Sci U S A. 2005. PMID: 16236721 Free PMC article.

9

Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactin.

McLoughlin SM, Kelleher NL. McLoughlin SM, et al. J Am Chem Soc. 2004 Oct 20;126(41):13265-75. doi: 10.1021/ja0470867. J Am Chem Soc. 2004. PMID: 15479080 Free PMC article.

10

Parallel interrogation of covalent intermediates in the biosynthesis of gramicidin S using high-resolution mass spectrometry.

Miller LM, Mazur MT, McLoughlin SM, Kelleher NL. Miller LM, et al. Among authors: mcloughlin sm. Protein Sci. 2005 Oct;14(10):2702-12. doi: 10.1110/ps.051553705. Protein Sci. 2005. PMID: 16195555 Free PMC article.

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