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Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC. Janda CY, et al. Among authors: zhong za. Nature. 2017 May 11;545(7653):234-237. doi: 10.1038/nature22306. Epub 2017 May 3. Nature. 2017. PMID: 28467818 Free PMC article.
Lrp5 functions in bone to regulate bone mass.
Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG. Cui Y, et al. Nat Med. 2011 Jun;17(6):684-91. doi: 10.1038/nm.2388. Epub 2011 May 22. Nat Med. 2011. PMID: 21602802 Free PMC article.
Wntless functions in mature osteoblasts to regulate bone mass.
Zhong Z, Zylstra-Diegel CR, Schumacher CA, Baker JJ, Carpenter AC, Rao S, Yao W, Guan M, Helms JA, Lane NE, Lang RA, Williams BO. Zhong Z, et al. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):E2197-204. doi: 10.1073/pnas.1120407109. Epub 2012 Jun 28. Proc Natl Acad Sci U S A. 2012. PMID: 22745162 Free PMC article.
LRP5 and LRP6 in development and disease.
Joiner DM, Ke J, Zhong Z, Xu HE, Williams BO. Joiner DM, et al. Trends Endocrinol Metab. 2013 Jan;24(1):31-9. doi: 10.1016/j.tem.2012.10.003. Trends Endocrinol Metab. 2013. PMID: 23245947 Free PMC article. Review.
Wnt signaling regulates pulp volume and dentin thickness.
Lim WH, Liu B, Cheng D, Hunter DJ, Zhong Z, Ramos DM, Williams BO, Sharpe PT, Bardet C, Mah SJ, Helms JA. Lim WH, et al. J Bone Miner Res. 2014 Apr;29(4):892-901. doi: 10.1002/jbmr.2088. J Bone Miner Res. 2014. PMID: 23996396 Free PMC article.
Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.
Valkenburg KC, Graveel CR, Zylstra-Diegel CR, Zhong Z, Williams BO. Valkenburg KC, et al. Cancers (Basel). 2011 Apr 19;3(2):2050-79. doi: 10.3390/cancers3022050. Cancers (Basel). 2011. PMID: 24212796 Free PMC article.
34 results