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In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Among authors: wu k. Nat Biotechnol. 2017 Jun;35(6):569-576. doi: 10.1038/nbt.3836. Epub 2017 May 1. Nat Biotechnol. 2017. PMID: 28459449 Free PMC article.
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz ÖH, Xue W, Katajisto P, Bhutkar A, Jacks T. Tammela T, et al. Among authors: wu k. Nature. 2017 May 18;545(7654):355-359. doi: 10.1038/nature22334. Epub 2017 May 10. Nature. 2017. PMID: 28489818 Free PMC article.
Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Among authors: wu k. Nat Biotechnol. 2017 Dec 8;35(12):1211. doi: 10.1038/nbt1217-1211a. Nat Biotechnol. 2017. PMID: 29220013
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.
Marjanovic ND, Hofree M, Chan JE, Canner D, Wu K, Trakala M, Hartmann GG, Smith OC, Kim JY, Evans KV, Hudson A, Ashenberg O, Porter CBM, Bejnood A, Subramanian A, Pitter K, Yan Y, Delorey T, Phillips DR, Shah N, Chaudhary O, Tsankov A, Hollmann T, Rekhtman N, Massion PP, Poirier JT, Mazutis L, Li R, Lee JH, Amon A, Rudin CM, Jacks T, Regev A, Tammela T. Marjanovic ND, et al. Among authors: wu k. Cancer Cell. 2020 Aug 10;38(2):229-246.e13. doi: 10.1016/j.ccell.2020.06.012. Epub 2020 Jul 23. Cancer Cell. 2020. PMID: 32707077 Free PMC article.
Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling.
Lähde M, Heino S, Högström J, Kaijalainen S, Anisimov A, Flanagan D, Kallio P, Leppänen VM, Ristimäki A, Ritvos O, Wu K, Tammela T, Hodder M, Sansom OJ, Alitalo K. Lähde M, et al. Among authors: wu k. Gastroenterology. 2021 Jan;160(1):245-259. doi: 10.1053/j.gastro.2020.09.011. Epub 2020 Sep 14. Gastroenterology. 2021. PMID: 32941878 Free article.
Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State.
Pitter KL, Grbovic-Huezo O, Joost S, Singhal A, Blum M, Wu K, Holm M, Ferrena A, Bhutkar A, Hudson A, Lecomte N, de Stanchina E, Chaligne R, Iacobuzio-Donahue CA, Pe'er D, Tammela T. Pitter KL, et al. Among authors: wu k. Cancer Res. 2022 Oct 4;82(19):3549-3560. doi: 10.1158/0008-5472.CAN-22-1742. Cancer Res. 2022. PMID: 35952360 Free PMC article.
A Python library for probabilistic analysis of single-cell omics data.
Gayoso A, Lopez R, Xing G, Boyeau P, Valiollah Pour Amiri V, Hong J, Wu K, Jayasuriya M, Mehlman E, Langevin M, Liu Y, Samaran J, Misrachi G, Nazaret A, Clivio O, Xu C, Ashuach T, Gabitto M, Lotfollahi M, Svensson V, da Veiga Beltrame E, Kleshchevnikov V, Talavera-López C, Pachter L, Theis FJ, Streets A, Jordan MI, Regier J, Yosef N. Gayoso A, et al. Among authors: wu k. Nat Biotechnol. 2022 Feb;40(2):163-166. doi: 10.1038/s41587-021-01206-w. Nat Biotechnol. 2022. PMID: 35132262 No abstract available.
Solid tumor growth depends on an intricate equilibrium of malignant cell states.
Torborg SR, Grbovic-Huezo O, Singhal A, Holm M, Wu K, Han X, Ho YJ, Haglund C, Mitchell MJ, Lowe SW, Dow LE, Pitter KL, Sanchez-Rivera FJ, Levchenko A, Tammela T. Torborg SR, et al. Among authors: wu k. bioRxiv [Preprint]. 2023 Dec 30:2023.12.30.573100. doi: 10.1101/2023.12.30.573100. bioRxiv. 2023. PMID: 38234855 Free PMC article. Preprint.
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