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Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma.
Puente J, Laínez N, Dueñas M, Méndez-Vidal MJ, Esteban E, Castellano D, Martinez-Fernández M, Basterretxea L, Juan-Fita MJ, Antón L, León L, Lambea J, Pérez-Valderrama B, Vázquez S, Suarez C, Del Muro XG, Gallardo E, Maroto JP, Samaniego ML, Suárez-Paniagua B, Sanz J, Paramio JM; SOGUG (Spanish Oncology Genitourinary Group). Puente J, et al. Among authors: paramio jm. Oncotarget. 2017 May 2;8(18):30410-30421. doi: 10.18632/oncotarget.16494. Oncotarget. 2017. PMID: 28423742 Free PMC article.
Transgenic mice expressing constitutively active Akt in oral epithelium validate KLFA as a potential biomarker of head and neck squamous cell carcinoma.
Moral M, Segrelles C, Martínez-Cruz AB, Lorz C, Santos M, García-Escudero R, Lu J, Buitrago A, Costa C, Saiz C, Ariza JM, Dueñas M, Rodriguez-Peralto JL, Martinez-Tello FJ, Rodriguez-Pinilla M, Sanchez-Cespedes M, Digiovanni J, Paramio JM. Moral M, et al. Among authors: paramio jm. In Vivo. 2009 Sep-Oct;23(5):653-60. In Vivo. 2009. PMID: 19779097 Free PMC article.
A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling.
Lorz C, García-Escudero R, Segrelles C, Garín MI, Ariza JM, Santos M, Ruiz S, Lara MF, Martínez-Cruz AB, Costa C, Buitrago-Pérez A, Saiz-Ladera C, Dueñas M, Paramio JM. Lorz C, et al. Among authors: paramio jm. Stem Cell Rev Rep. 2010 Jun;6(2):162-77. doi: 10.1007/s12015-010-9139-0. Stem Cell Rev Rep. 2010. PMID: 20376578 Free PMC article.
EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.
Bornachea O, Santos M, Martínez-Cruz AB, García-Escudero R, Dueñas M, Costa C, Segrelles C, Lorz C, Buitrago A, Saiz-Ladera C, Agirre X, Grande T, Paradela B, Maraver A, Ariza JM, Prosper F, Serrano M, Sánchez-Céspedes M, Paramio JM. Bornachea O, et al. Among authors: paramio jm. Sci Rep. 2012;2:434. doi: 10.1038/srep00434. Epub 2012 May 31. Sci Rep. 2012. PMID: 22666537 Free PMC article.
Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.
Dueñas M, Santos M, Aranda JF, Bielza C, Martínez-Cruz AB, Lorz C, Taron M, Ciruelos EM, Rodríguez-Peralto JL, Martín M, Larrañaga P, Dahabreh J, Stathopoulos GP, Rosell R, Paramio JM, García-Escudero R. Dueñas M, et al. Among authors: paramio jm. PLoS One. 2012;7(8):e42494. doi: 10.1371/journal.pone.0042494. Epub 2012 Aug 7. PLoS One. 2012. PMID: 22880004 Free PMC article.
A humanized mouse model of HPV-associated pathology driven by E7 expression.
Buitrago-Pérez Á, Hachimi M, Dueñas M, Lloveras B, Santos A, Holguín A, Duarte B, Santiago JL, Akgül B, Rodríguez-Peralto JL, Storey A, Ribas C, Larcher F, del Rio M, Paramio JM, García-Escudero R. Buitrago-Pérez Á, et al. Among authors: paramio jm. PLoS One. 2012;7(7):e41743. doi: 10.1371/journal.pone.0041743. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22911850 Free PMC article.
A novel tumor suppressor network in squamous malignancies.
Costa C, Santos M, Segrelles C, Dueñas M, Lara MF, Agirre X, Prosper F, García-Escudero R, Paramio JM. Costa C, et al. Among authors: paramio jm. Sci Rep. 2012;2:828. doi: 10.1038/srep00828. Epub 2012 Nov 9. Sci Rep. 2012. PMID: 23145321 Free PMC article.
p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.
Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. Saiz-Ladera C, et al. Among authors: paramio jm. Oncogene. 2014 Sep 11;33(37):4599-4612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14. Oncogene. 2014. PMID: 24121270 Free PMC article.
149 results