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Identification of 3-substituted-6-(1-(1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)ethyl)quinoline derivatives as highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitors via metabolite profiling-based structural optimization.
Zhao F, Zhang LD, Hao Y, Chen N, Bai R, Wang YJ, Zhang CC, Li GS, Hao LJ, Shi C, Zhang J, Mao Y, Fan Y, Xia GX, Yu JX, Liu YJ. Zhao F, et al. Among authors: wang yj. Eur J Med Chem. 2017 Jul 7;134:147-158. doi: 10.1016/j.ejmech.2017.03.085. Epub 2017 Apr 4. Eur J Med Chem. 2017. PMID: 28411455
4,631 results